Results 111 to 120 of about 7,119,691 (324)
Bayesian model comparison based on expected posterior priors for discrete decomposable graphical models [PDF]
The implementation of the Bayesian paradigm to model comparison can be problematic. In particular, prior distributions on the parameter space of each candidate model require special care.
Guido Consonni, Monia Lupparelli
core
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Frontiers in Public Health, 2014 Many multiple testing procedures (MTP) have been developed in recent years. Among these new procedures, the graphical approach is flexible and easy to communicate with non-statisticians.
Naitee eTing, Bushi eWang
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Dynamic k-Struve Sumudu solutions for fractional kinetic equations
Advances in Difference Equations, 2017 In this present study, we investigate the solutions for fractional kinetic equations involving k-Struve function using the Sumudu transform. The graphical interpretations of the solutions involving k-Struve function and its comparison with generalized ...
Kottakkaran Sooppy Nisar +1 more
doaj +1 more source
A GCM simulation of the earth-atmosphere radiation balance for winter and summer [PDF]
The radiation balance of the earth-atmosphere system simulated by using the general circulation model (GCM) of the Laboratory for Atmospheric Sciences (GLAS) is examined in regards to its graphical distribution, zonally-averaged distribution, and global ...
Wu, M. L. C.
core +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
, 2017 . Plant root water uptake (RWU) has been documented for the past five decades from water stable isotopic analysis. By comparing the (hydrogen or oxygen) stable isotopic compositions of plant xylem water to those of potential contributive water sources (e.
Y. Rothfuss, M. Javaux
semanticscholar +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source