Results 101 to 110 of about 115,881,303 (256)
Simulating interventions in graphical chain models for longitudinal data [PDF]
Simulating the outcome of an intervention is a central problem in many fields as this allows decision-makers to quantify the effect of any given strategy and, hence, to evaluate different schemes of actions.
Peter W. F. Smith +2 more
core
How to Improve the Monitoring of Subjective Analytical Methods and Assessors - The Case of Wine
Due to possible various physiological errors in sensory testing, regardless of knowledge and experience, it is necessary to control the results and assessors. This paper aims the possibility of some statistical tools based on laboratory control charts to
Ivana Alpeza, Ivna Linke, Biserka Runje
doaj
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
The R Commander: A Basic-Statistics Graphical User Interface to R [PDF]
Unlike S-PLUS, R does not incorporate a statistical graphical user interface (GUI), but it does include tools for building GUIs. Based on the tcltk package (which furnishes an interface to the Tcl/Tk GUI toolkit), the Rcmdr package provides a basic ...
John Fox
core
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Background Congenital anomalies (CA), ICD-10 Q00–Q99 codes, are major causes of infant morbidity and mortality, but national assessments remain limited in countries without integrated birth defect surveillance.
Fabricio González-Andrade
doaj +1 more source
Analysis of the Users’ Understanding of Icons in Graphical User Interface of Simorgh Software [PDF]
Purpose: This research is devoted to study the icons in graphical user interface of Simorgh library software and analyze the users’ understanding of and interaction with this software in Birjand University.
Mohammad-Javad Hashemzadeh +1 more
doaj
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source

