Results 81 to 90 of about 115,881,303 (256)
Medical graduate views on statistical learning needs for clinical practice: a comprehensive survey
BMC Medical Education, 2019 Background This paper seeks to contribute to a reputable evidence base for required competencies across different topics in statistics and probability (statistical topics) in preparing medical graduates for clinical practice.
Margaret MacDougall +2 more
doaj +1 more source
BMC Medical Research Methodology, 2011 Background Clinical researchers have often preferred to use a fixed effects model for the primary interpretation of a meta-analysis. Heterogeneity is usually assessed via the well known Q and I2 statistics, along with the random effects estimate they ...
Tierney Jayne F +3 more
doaj +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
On Sample Size and Quick Simultaneous Confidence Interval Estimations for Multinomial Proportions
, 1998 Journal of Computational and Graphical Statistics72212 ...
KWONG, Koon Shing, Kwong, K.-S.
core +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Inference in Graphical Gaussian Models with Edge and Vertex Symmetries with the gRc Package for R [PDF]
In this paper we present the R package gRc for statistical inference in graphical Gaussian models in which symmetry restrictions have been imposed on the concentration or partial correlation matrix.
Steffen L. Lauritzen, Søren Højsgaard
core
Unit 099 - Detecting and Evaluating Errors by Graphical Methods [PDF]
, 2000 This unit discusses error detection and evaluation by graphical methods. It describes example methods used in statistics, cartography and GIS; challenges including issues in graphic design, metadata, error analysis and detection; techniques for analyzing
Hunter, Gary +2 more
core +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Integrated Information System for Demographic Statistics 'ESGRAON-TDS' in Bulgaria [PDF]
In this paper we describe the Bulgarian statistical system that provides unique research possibilities for demographic analyses. In particular, we review the methodology, structure and informational flows for population registration and the registration ...
Mariana Dimova +2 more
core
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source