Results 141 to 150 of about 22,758,545 (367)

High dimensional Sparse Gaussian Graphical Mixture Model

, 2013
This paper considers the problem of networks reconstruction from heterogeneous data using a Gaussian Graphical Mixture Model (GGMM). It is well known that parameter estimation in this context is challenging due to large numbers of variables coupled with ...
Lotsi, Anani, Wit, Ernst
core   +1 more source

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

Molecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou, Aliki Ntzifa, Victoria Tserpeli, Ioanna Balgkouranidou, Alkistis Papatheodoridi, Evangelia Razis, Helena Linardou, Christos Papadimitriou, Amanda Psyrri, Flora Zagouri, Stylianos Kakolyris, Evi Lianidou   +11 more
wiley   +1 more source

Volume staging for arteriovenous malformation SRS treatment using VMAT

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Volume staging involves dividing the target volume into smaller parts and treating each part separately. In this study, the feasibility of volume‐staged stereotactic radiosurgery (VS‐SRS) on a linear accelerator using volumetric modulated arc therapy (VMAT) and a frameless patient positioning system is investigated.
Claudia Mendez, Ermias Gete
wiley   +1 more source

Graphical modelling for geographic explanation [PDF]

, 1997
Directly interpretative spatial knowledge which may be of value to the user resides in the possible arrangements underpinned by geographical objects. Until now, the meaning of geographic information was unveiled through the eye-brain apparatus of the user.
Cheylan, Jean-Paul, Libourel Rouge, Thérèse, Mende, Cornelius   +2 more
openaire   +4 more sources

nference in Graphical Gaussian Models with Edge and Vertex Symmetries with the gRc Package for R

Journal of Statistical Software, 2007
In this paper we present the R package gRc for statistical inference in graphical Gaussian models in which symmetry restrictions have been imposed on the concentration or partial correlation matrix.
Søren Højsgaard, Steffen L. Lauritzen
doaj  

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

Molecular Oncology, EarlyView.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa, Zdenka Herudkova, Jan Hyl, Jakub Vlazny, Filip Sokol, Kvetoslava Matulova, Adam Folta, Jakub Hynst, Lucy Vojtova, Leos Kren, Martin Repko, Zdenek Racil, Jiri Mayer, Martin Culen   +13 more
wiley   +1 more source

Digital radiography image quality evaluation using various phantoms and software

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose To investigate the effect of the exposure parameters on image quality (IQ) metrics of phantom images, obtained automatically using software or from visual evaluation. Methods Three commercial phantoms and a homemade phantom constructed according to the instructions given in the IAEA Human Health Series No.
Ioannis A. Tsalafoutas, Shady AlKhazzam, Virginia Tsapaki, Huda AlNaemi, Mohammed Hassan Kharita   +4 more
wiley   +1 more source

Graphical Independence Networks with the gRain Package for R

Journal of Statistical Software, 2012
In this paper we present the R package gRain for propagation in graphical independence networks (for which Bayesian networks is a special instance). The paper includes a description of the theory behind the computations.
Soren Hojsgaard
doaj  

Polyfunctional CD8+CD226+RUNX2hi effector T cells are diminished in advanced stages of chronic lymphocytic leukemia

Molecular Oncology, EarlyView.
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar, Shima Shahbaz, Anthea C. Peters, Spencer B. Gibson, Shokrollah Elahi   +4 more
wiley   +1 more source

EPSOM-Hyb: A General Purpose Estimator of Log-Marginal Likelihoods with Applications in Probabilistic Graphical Models

Algorithms
We consider the estimation of the marginal likelihood in Bayesian statistics, with primary emphasis on Gaussian graphical models, where the intractability of the marginal likelihood in high dimensions is a frequently researched problem.
Eric Chuu, Yabo Niu, Anirban Bhattacharya, Debdeep Pati   +3 more
doaj   +1 more source