Results 161 to 170 of about 418,262 (313)

SpiderLearner: An ensemble approach to Gaussian graphical model estimation. [PDF]

open access: yesStat Med, 2023
Shutta KH   +3 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Comparison of simple graphical process models

open access: yesJournal of Information and Organizational Sciences, 2012
Comparing structure of graphical process models can reveal different variations of processes. Since most contemporary norms for process modeling lean on directed connectivity of objects in the model, their connections structure form sequences which can ...
Katarina Tomicic-Pupek   +2 more
doaj  

On the Pragmatics of Graphical Modeling.

open access: yes, 2011
Graphical models help to understand complex systems. However, with the user interaction paradigms established today, activities such as creating, maintaining or browsing graphical models can be very tedious. This thesis presents an approach to enhance productivity by focusing on the pragmatics of model-based design.
openaire   +3 more sources

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

An Optimal Probabilistic Graphical Model for Point Set Matching

open access: yes, 2004
An Optimal Probabilistic Graphical Model for Point Set ...
TS Caetano (14540141)   +2 more
core  

Spectron: Graphical Model for Interacting With Timbre

open access: yesTecnoLógicas, 2009
The algorithms for creating and manipulating sound by electronic or digital means have grown in number and complexity since the creation of the first analog synthesizers.
Daniel Gómez
doaj  

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