Results 171 to 180 of about 422,581 (268)

Bayesian causal graphical model for joint Mendelian randomization analysis of multiple exposures and outcomes. [PDF]

Am J Hum Genet
Zuber V, Cronjé T, Cai N, Gill D, Bottolo L.   +4 more
europepmc   +1 more source

Dietary networks identified by Gaussian graphical model and general and abdominal obesity in adults. [PDF]

Nutr J, 2021
Jayedi A, Janbozorgi N, Djafarian K, Yekaninejad MS, Shab-Bidar S.   +4 more
europepmc   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Network Approach to Evaluate the Effect of Diet on Stroke or Myocardial Infarction Using Gaussian Graphical Model. [PDF]

Nutrients
Lailo JM, Shin J, Menichetti G, Lee SA.
europepmc   +1 more source

MODEL FREE ESTIMATION OF GRAPHICAL MODEL USING GENE EXPRESSION DATA. [PDF]

Ann Appl Stat, 2021
Yang J, Liu Y, Liu Y, Sun W.
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

A probabilistic graphical model for estimating selection coefficients of nonsynonymous variants from human population sequence data. [PDF]

Nat Commun
Zhao Y, Lan T, Zhong G, Hagen J, Pan H, Chung WK, Shen Y.   +6 more
europepmc   +1 more source

Inter-Subject Analysis: A Partial Gaussian Graphical Model Approach. [PDF]

J Am Stat Assoc, 2021
Ma C, Lu J, Liu H.
europepmc   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

sPGGM: a sample-perturbed Gaussian graphical model for identifying pre-disease stages and signaling molecules of disease progression. [PDF]

Natl Sci Rev
Zhong J, Li J, Gu X, Ding D, Ling F, Chen P, Liu R.   +6 more
europepmc   +1 more source