Results 61 to 70 of about 1,309,109 (281)

Articulated Pose Estimation by a Graphical Model with Image Dependent Pairwise Relations [PDF]

open access: yes, 2014
We present a method for estimating articulated human pose from a single static image based on a graphical model with novel pairwise relations that make adaptive use of local image measurements.
Chen, Xianjie, Yuille, Alan
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Classification of LiDAR Point Clouds Using Supervoxel-Based Detrended Feature and Perception-Weighted Graphical Model

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2020
Interpretation of 3-D scene through LiDAR point clouds has been a hot research topic for decades. To utilize measured points in the scene, assigning unique tags to the points of the scene with labels linking to individual objects plays a crucial role in ...
Yusheng Xu   +6 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Efficient Proximal Gradient Algorithms for Joint Graphical Lasso

open access: yesEntropy, 2021
We consider learning as an undirected graphical model from sparse data. While several efficient algorithms have been proposed for graphical lasso (GL), the alternating direction method of multipliers (ADMM) is the main approach taken concerning joint ...
Jie Chen, Ryosuke Shimmura, Joe Suzuki
doaj   +1 more source

On combining the facial movements of a talking head [PDF]

open access: yes, 2005
We present work on Obie, an embodied conversational agent framework. An embodied conversational agent, or talking head, consists of three main components. The graphical part consists of a face model and a facial muscle model.
Bui, T.D.   +3 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Graphical LASSO Based Model Selection for Time Series

open access: yes, 2014
We propose a novel graphical model selection (GMS) scheme for high-dimensional stationary time series or discrete time process. The method is based on a natural generalization of the graphical LASSO (gLASSO), introduced originally for GMS based on i.i.d.
Görtz, Norbert   +2 more
core   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Loop Calculus for Non-Binary Alphabets using Concepts from Information Geometry [PDF]

open access: yes, 2014
The Bethe approximation is a well-known approximation of the partition function used in statistical physics. Recently, an equality relating the partition function and its Bethe approximation was obtained for graphical models with binary variables by ...
Mori, Ryuhei
core   +1 more source

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