Results 71 to 80 of about 1,309,109 (281)
Algebraic Aspects of Conditional Independence and Graphical Models
, 2017 This chapter of the forthcoming Handbook of Graphical Models contains an overview of basic theorems and techniques from algebraic geometry and how they can be applied to the study of conditional independence and graphical models.
Kahle, Thomas +2 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Investigating effective wayfinding in airports: a Bayesian network approach
Transport, 2014 Effective wayfinding is the successful interplay of human and environmental factors resulting in a person successfully moving from their current position to a desired location in a timely manner. To date this process has not been modelled to reflect this
Anna Charisse Farr +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
High-Dimensional Graphical Model Search with the gRapHD R Package
Journal of Statistical Software, 2010 This paper presents the R package gRapHD for efficient selection of high-dimensional undirected graphical models. The package provides tools for selecting trees, forests, and decomposable models minimizing information criteria such as AIC or BIC, and for
Gabriel C. G. Abreu +2 more
doaj
Frontiers in Psychology, 2019 Exploratory analyses are an important first step in psychological research, particularly in problem-based research where various variables are often included from multiple theoretical perspectives not studied together in combination before.
Nitin Bhushan +5 more
doaj +1 more source
Markov Properties for Graphical Models with Cycles and Latent Variables [PDF]
, 2017 We investigate probabilistic graphical models that allow for both cycles and latent variables. For this we introduce directed graphs with hyperedges (HEDGes), generalizing and combining both marginalized directed acyclic graphs (mDAGs) that can model ...
Forré, Patrick, Mooij, Joris M.
core +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Cavity approximation for graphical models [PDF]
Physical Review E, 2007 Extension to factor graphs and comments on related work ...
Rizzo, T. +3 more
openaire +4 more sources