Results 91 to 100 of about 1,036,354 (257)
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Adaptive mesh-aligned Gaussian Splatting for monocular human avatar reconstruction
Graphical ModelsVirtual human avatars are essential for applications such as gaming, augmented reality, and virtual production. However, existing methods struggle to achieve high fidelity reconstruction from monocular input while keeping hardware costs low.
Hai Yuan +6 more
doaj +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
GPU-accelerated rendering of vector strokes with piecewise quadratic approximation
Graphical ModelsVector graphics are widely used in areas such as logo design and digital painting, including both stroked and filled paths as primitives. GPU-based rendering for filled paths already has well-established solutions. Due to the complexity of stroked paths,
Xuhai Chen +4 more
doaj +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Geometry of the visual cortex with applications to image inpainting and enhancement
Graphical ModelsEquipping the rototranslation group SE(2) with a sub-Riemannian structure inspired by the visual cortex V1, we propose algorithms for image inpainting and enhancement based on hypoelliptic diffusion. We innovate on previous implementations of the methods
Francesco Ballerin, Erlend Grong
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Computing medial axis of a simple polygon in linear time based on R-L sequence
Graphical ModelsMedial axis computation has wide applications in pattern recognition, image processing, finite element mesh generation, and CNC tool path extraction. Aiming to explore intrinsic geometric attributes of the medial axis of a simple polygon which can be ...
Hongyu Chen, Xiaodiao Chen, Yizhao Xue
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Design method of porous scaffold based on TPMS and KM growth function
Graphical ModelsAdditive manufacturing technology, as a cutting-edge manufacturing process, has shown great potential in the preparation of 3D tissue engineering scaffolds with complex pore structures.
Yi Zhang, Jiong Liu, Quan Qi
doaj +1 more source