Results 141 to 150 of about 317,964 (264)

Causal Graphical Models and Their Applications. [PDF]

Entropy (Basel)
Sucar LE, Danks D.
europepmc   +1 more source

Directed Graphical Models and Causal Discovery for Zero-Inflated Data. [PDF]

Proc Mach Learn Res, 2023
Yu S, Drton M, Shojaie A.
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Lipid Class Prediction from MS1 Data using Gaussian Graphical Models. [PDF]

Anal Chem
Rix T, Sands CJ, Villaseñor A, Gradillas A, Barbas C, Chekmeneva E, Want EJ, Ebbels TMD.   +7 more
europepmc   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Simultaneous clustering and estimation of networks in multiple graphical models. [PDF]

Biostatistics
Li G, Wang M.
europepmc   +1 more source

Tree-based Node Aggregation in Sparse Graphical Models. [PDF]

J Mach Learn Res, 2022
Wilms I, Bien J.
europepmc   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Learning Gaussian Graphical Models from Correlated Data. [PDF]

Front Syst Biol
Song Z, Gunn S, Monti S, Peloso GM, Liu CT, Lunetta K, Sebastiani P.   +6 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source