Results 151 to 160 of about 325,747 (265)

Learning Gaussian Graphical Models from Correlated Data. [PDF]

Front Syst Biol
Song Z, Gunn S, Monti S, Peloso GM, Liu CT, Lunetta K, Sebastiani P.   +6 more
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Bayes Factor Tests for Group Differences in Ordinal and Binary Graphical Models. [PDF]

Psychometrika
Marsman M, Waldorp LJ, Sekulovski N, Haslbeck JMB.   +3 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Population-level analysis of chronic disease multimorbidity at older ages across time using mixed graphical models. [PDF]

Arch Public Health
Dang LHK, Caranci N, Fortuna D, Roli G, Rettaroli R, Miglio R.   +5 more
europepmc   +1 more source

DRAGON: Determining Regulatory Associations using Graphical models on multi-Omic Networks. [PDF]

Nucleic Acids Res, 2023
Shutta KH, Weighill D, Burkholz R, Guebila MB, DeMeo DL, Zacharias HU, Quackenbush J, Altenbuchinger M.   +7 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Understanding multimorbidity: insights with graphical models. [PDF]

BMC Med Res Methodol
Banzato E, Roverato A, Buja A, Boccuzzo G.   +3 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Bayesian Graphical Models for Multiscale Inference in Medical Image-Based Joint Degeneration Analysis. [PDF]

Diagnostics (Basel)
Kumar R, Marla K, Ravi P, Sporn K, Srinivas R, Vaja S, Ngo A, Tavakkoli A.   +7 more
europepmc   +1 more source