Results 111 to 120 of about 1,973,658 (304)

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Graphical representation of chemical periodicity of main elements through boxplot

Educación Química, 2018
Graphics play an important role in data analysis. Boxplots are powerful graphical representation of data that gives an overview and a numerical summary of a data set. In this paper boxplots are used to analyze the periodic trends of main elements.
João Elias Vidueira Ferreira, Maria Tayane Silva Pinheiro, Wagner Roberto Santos dos Santos, Rodrigo da Silva Maia   +3 more
doaj   +1 more source

Engineering indel and substitution variants of diverse and ancient enzymes using Graphical Representation of Ancestral Sequence Predictions (GRASP). [PDF]

PLoS Comput Biol, 2022
Foley G, Mora A, Ross CM, Bottoms S, Sützl L, Lamprecht ML, Zaugg J, Essebier A, Balderson B, Newell R, Thomson RES, Kobe B, Barnard RT, Guddat L, Schenk G, Carsten J, Gumulya Y, Rost B, Haltrich D, Sieber V, Gillam EMJ, Bodén M.   +21 more
europepmc   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

METAGRAPH VISUALIZATION METHOD [PDF]

Научно-технический вестник информационных технологий, механики и оптики, 2014
Analysis of visualization techniques for various types of graphs is done. Conclusion about the relevance of method development for metagraph visualizing is made. The paper deals with issues that arise when solving the problem of metagraph visualization,
O. S. Kryvenko
doaj  

Detection of intra-family coronavirus genome sequences through graphical representation and artificial neural network. [PDF]

Expert Syst Appl, 2022
Paul T, Vainio S, Roning J.
europepmc   +1 more source

GROOVE - Graphical Representation of Overlap for OVErviews

GROOVE - Graphical Representation of Overlap for ...
Xavier Bonfill, Eva Madrid, Nicolas Meza, Shrikant Bangdiwala, Ena Niño de Guzmán, Gerard Urrutia, Javier Bracchiglione   +6 more
core   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

Revisiting the Open Sampling format: Improving risky choices through a novel graphical representation. [PDF]

Psychon Bull Rev, 2022
Tiede KE, Henninger F, Kieslich PJ.
europepmc   +1 more source

Graphical representation of KOG function distribution.

, 2015
Graphical representation of KOG function distribution.
D. R. Bharadwaj (750296), Anjali Shukla (750294), V. K. Singh (750295), Ashutosh Rai (750297), Raja Mugasimangalam (714385), P. S. Naik (750301), Rajesh Kumar (72124), Sriram Parameswaran (750299), Major Singh (750300), A. K. Rai (750298)   +9 more
core   +1 more source