Results 121 to 130 of about 1,973,658 (304)

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

open access: yesMolecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau   +9 more
wiley   +1 more source

Pre-Service Mathematics Teachers’ Transformation Skills: A Focus on Algebraic and Graphical Representations

open access: yesTrends in Higher Education
The aim of this study is to investigate the skills of pre-service mathematics teachers in transforming between algebraic and graphical representations of one- and two-variable relations. This study adopted a qualitative research approach and was designed
Muhammet Doruk, Gül Mine Bayram Gün
doaj   +1 more source

A Novel Graphical Technique for Combinational Logic Representation and Optimization

open access: yesComplexity, 2017
We present a new technique for defining, analysing, and simplifying digital functions, through hand-calculations, easily demonstrable therefore in the classrooms. It can be extended to represent discrete systems beyond the Boolean logic.
Vedhas Pandit, Björn Schuller
doaj   +1 more source

Graphical representation of the confirmatory factor analysis.

open access: yes, 2019
Graphical representation of the confirmatory factor analysis.
Stefania Mannarini (593621)   +7 more
core   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

open access: yesMolecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński   +12 more
wiley   +1 more source

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

open access: yesMolecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis   +20 more
wiley   +1 more source

Graphical representation of Rac regulatory mechanism.

open access: yes, 2012
Graphical representation of Rac regulatory mechanism.
John Konvalina (126372)   +11 more
core   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

open access: yesMolecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi   +2 more
wiley   +1 more source

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