CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee +3 more
wiley +1 more source
From Fragment to One Piece: A Review on AI-Driven Graphic Design. [PDF]
Zou X, Zhang W, Zhao N.
europepmc +1 more source
Application of Interactive Graphics Technology to the Problem of Standardizing Diagnosis and Therapy of Schizophrenic Patients [PDF]
W. Sidoruk
openalex +1 more source
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
Dynamical study of optical soliton solutions of time-fractional perturbed model in ultrafast optical fibers. [PDF]
Ouahid L +7 more
europepmc +1 more source
Microprocessor software applications in color graphics [PDF]
Fred Rodgers
openalex +1 more source
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
Evidence on Methods for Communicating Health-Related Probabilities: Comparing the Making Numbers Meaningful Systematic Review to the 2021 IPDAS Evidence Paper Recommendations. [PDF]
Zikmund-Fisher BJ, Benda NC, Ancker JS.
europepmc +1 more source
Computer graphics in an automatic aircraft landing system [PDF]
E. H. Reitan, S. H. Saib
openalex +1 more source
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp +13 more
wiley +1 more source

