Results 61 to 70 of about 2,332,619 (281)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Embedding Graphs into Embedded Graphs [PDF]

open access: yesAlgorithmica, 2020
A (possibly denerate) drawing of a graph $G$ in the plane is approximable by an embedding if it can be turned into an embedding by an arbitrarily small perturbation. We show that testing, whether a straight-line drawing of a planar graph $G$ in the plane is approximable by an embedding, can be carried out in polynomial time, if a desired embedding of ...
openaire   +4 more sources

Biclique Graphs of K3-free Graphs and Bipartite Graphs

open access: yesProcedia Computer Science, 2021
A biclique of a graph is a maximal complete bipartite subgraph. The biclique graph of a graph $G$, $KB(G)$, defined as the intersection graph of the bicliques of $G$, was introduced and characterized in 2010. However, this characterization does not lead to polynomial time recognition algorithms.
Groshaus, Marina   +1 more
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Relating threshold tolerance graphs to other graph classes [PDF]

open access: yes, 2014
A graph G=(V, E) is a threshold tolerance if it is possible to associate weights and tolerances with each node of G so that two nodes are adjacent exactly when the sum of their weights exceeds either one of their tolerances.
CALAMONERI, Tiziana, SINAIMERI, BLERINA
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

The Interpreting Ability on Science Kinematics Graphs of Senior High School Students in South Sulawesi, Indonesia

open access: yesJurnal Pendidikan IPA Indonesia, 2020
This research was a descriptive case study. The purpose of this research was to describe the student’s ability to interpret the kinematics graph. The subjects of the study were 347 students of class XI science in the even semester of 2018/2019 in Luwu ...
B. D. Amin   +5 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Geometric Biplane Graphs I: Maximal Graphs [PDF]

open access: yesGraphs and Combinatorics, 2015
We study biplane graphs drawn on a finite planar point set $S$ in general position. This is the family of geometric graphs whose vertex set is $S$ and can be decomposed into two plane graphs. We show that two maximal biplane graphs---in the sense that no edge can be added while staying biplane---may differ in the number of edges, and we provide an ...
Garcia Olaverri, Alfredo Martin   +7 more
openaire   +5 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

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