Results 41 to 50 of about 959,665 (330)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Tomb number 2 of the Church of St. Michael in Mornago (Varese, Italy). Anthropological and archaeological study of medieval funeral remains [PDF]

open access: yes, 2017
The current paper aims to present the archaeological and anthropological results of the investigation conducted on a medieval burial which presents several features that recall the Longobard culture.
Badino, Paola   +2 more
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Shell and glass beads from the tombs of Kindoki, Mbanza Nsundi, Lower Congo [PDF]

open access: yes, 2014
The ancient Kingdom of Kongo originated in Central Africa in the 14th century. In the 15th century, the Portuguese organized tight contacts with the Bakongo.
Bostoen, Koen   +5 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Revisiting Reconstruction of the Early Nomadic Social Structure: Children’s Burials (Southern Urals, 6th – 3rd Centuries BC)

open access: yesНижневолжский археологический вестник, 2023
The study concerns the children as one of the social and demographic age groups that formed the early nomads‘ social structure. Burials of two chronological periods were studied: Sauromatian (late 6th – first half of 5th centuries BC) and Early ...
Natalia Berseneva
doaj   +1 more source

The Changing Understanding of North American Archaeology and Native American Heritage [PDF]

open access: yes, 2011
This article explores the evolving ways in which anthropologists, archaeologists, and the United States government have viewed Native American cultural heritage, especially in terms of burials and grave goods.
Bourgault, Ashley
core   +1 more source

Disappearance of grave goods:

open access: yes, 2023
ABOUT THE SITE The Institute of Archaeology (Zagreb) has been excavating the stratified site of “Old Town” in the center of Ivanec, a small town in northwestern Croatia, which has yielded evidence of continuous human use from antiquity to the 20th century.
Belaj, Juraj, Sirovica, Filomena
openaire   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

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