Results 41 to 50 of about 8,923 (294)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Revisiting Reconstruction of the Early Nomadic Social Structure: Children’s Burials (Southern Urals, 6th – 3rd Centuries BC)

open access: yesНижневолжский археологический вестник, 2023
The study concerns the children as one of the social and demographic age groups that formed the early nomads‘ social structure. Burials of two chronological periods were studied: Sauromatian (late 6th – first half of 5th centuries BC) and Early ...
Natalia Berseneva
doaj   +1 more source

Grave Goods:Objects and Death in Later Prehistoric Britain

open access: yes, 2021
Britain is internationally renowned for the high quality and exquisite crafting of its later prehistoric grave goods (c. 4000 BC to AD 43). Many of prehistoric Britain's most impressive artefacts have come from graves.
Cooper, Anwen   +5 more
core  

Kingston Down Grave 216

open access: yes, 2021
Tumulus as the last; the grave about three feet deep; feet to the east. Bones pretty entire; no appearance of a coffin. The blades of two knives, a larger and a smaller oval plate of iron, through which the strig of the greater knife was riveted when ...
Helena Hamerow (11585575)
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Despre cele două morminte din tell-ul de la Dridu

open access: yesMateriale și Cercetări Arheologice, 2015
Two inhumation graves (M. 1 and M. 2) were found in 1958, buried inside of a so-called tell, situated north of the medieval settlement. The two funerary structures were briefly described and published without any kind of illustration.
Oța, L., Georgescu, M., Baltă, Z.
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

On the edge of the eurasian steppes: the sarmatian culture in the 1st–3rd centuries ad east of the Carpathians

open access: yesПоволжская археология
The paper analyses the Sarmatian culture east of the Carpathians during the 1st-3rd centuries AD, shedding light on their burial practices, artefacts, and socio-economic interactions.
Grumeza Lavinia, Cojocaru Victor
doaj   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

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