Results 91 to 100 of about 9,625,606 (401)
Advanced Biology, EarlyView.The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran +5 more
wiley +1 more source
PAMJ Clinical Medicine, 2020 Graves´ disease (GD) is an autoimmune thyroid disease first described by Robert Graves in 1835. Patients with GD usually present with symptoms such as heat intolerance, palpitations, tremors, and weight loss.
Khaled Elmezughi +4 more
doaj +1 more source
Advanced Biology, EarlyView.A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso +5 more
wiley +1 more source
Acta Medica IranicaSelenium, a trace element present in specific selenoproteins, is essential for thyroid hormone metabolism. Selenium is also an antioxidant with immunosuppressive properties and may help in managing thyroid autoimmune diseases, including Graves’ (GD ...
Vahab Fatourechi, Hassan M. Heshmati
doaj +1 more source
Death by Suicide in Graves' Disease and Graves' Orbitopathy: A Nationwide Danish Register Study.
Thyroid, 2017 BACKGROUND Graves' disease (GD) is associated with excess morbidity and mortality, but little is known about unnatural manners of death and the potential relation with Graves' orbitopathy (GO).
Charlotte Ferløv-Schwensen +2 more
semanticscholar +1 more source
Advanced Biology, EarlyView.The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali +5 more
wiley +1 more source
Association between thymic hyperplasia and serum calcium level in Graves’ disease
BMC Endocrine DisordersBackground Graves' disease increases bone resorption in hyperthyroidism, leading to elevated serum calcium levels and a negative bone balance. Thymic hyperplasia is observed in some Graves' disease patients.
Jing Zeng, Lan Li, Dong Wei
doaj +1 more source
Overweight as a biomarker for concomitant thyroid cancer in patients with Graves’ disease
Frontiers in EndocrinologyThe incidence of concomitant thyroid cancer in Graves’ disease varies and Graves’ disease can make the diagnosis and management of thyroid nodules more challenging. Since the majority of Graves’ disease patients primarily received non-surgical treatment,
Joonseon Park +4 more
doaj +1 more source
Thyroid, 2017 BACKGROUND Current surgical indications for Graves' disease include intractability to medical and/or radioablative therapy, compressive symptoms, and worsening ophthalmopathy.
G. Rubio +5 more
semanticscholar +1 more source