Results 141 to 150 of about 374,026 (349)

Two Cases of Graves’ Disease Presenting with Unilateral Involvement of the Thyroid Gland

open access: yesEndocrinology Research and Practice, 2007
Graves’ disease is an autoimmune disorder of the thyroid which is characterized by hyperthyroidism and frequently accompanying diffuse goiter. Thyroid scan reveals diffuse bilateral increased uptake of radioisotopes. Unilateral involvement of the thyroid
Gürcan Kısakol   +3 more
doaj  

No evidence of a significant role for CTLA-4 in multiple sclerosis [PDF]

open access: yes, 2006
Variation in the cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) gene plays a significant role in determining susceptibility to autoimmune thyroid disease and type 1 diabetes. Its role in multiple sclerosis is more controversial. In order to explore
Compston, A   +7 more
core  

De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning

open access: yesAdvanced Science, EarlyView.
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li   +23 more
wiley   +1 more source

Nicotinamide and Pyridoxine Supplementation Enhances Muscle Stem Cell Activity and Muscle Regeneration in Humans: A Randomized Placebo‐Controlled Clinical Trial of High Force Eccentric Contraction Recovery in Healthy Young Men

open access: yesAdvanced Science, EarlyView.
In a randomized clinical trial, we test the potential of combined nicotinamide (NAM) and pyridoxine (PN) to improve muscle recovery through muscle stem cell (MuSC) activity. Daily oral NAM and PN supplementation after high intensity muscle contractions enhances MuSC activation and differentiation, and accelerates muscle regeneration, providing new ...
Grith Højfeldt   +14 more
wiley   +1 more source

Hyperthyroid heart disease: Diagnostic and therapeutic aspects [PDF]

open access: yes, 1990
Reinwein, Dankwart   +2 more
core   +1 more source

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

open access: yesAdvanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak   +9 more
wiley   +1 more source

Modulation of class-II antigen expression in human thyroid epithelial cell cultures [PDF]

open access: yes, 1987
Arnholdt, H.   +4 more
core   +1 more source

Spectrum, Autumn 1989 [PDF]

open access: yes, 1989
Spectrum was a newsletter for students, faculty, staff and alumni of the Henry M.
Frankl, Spencer N.
core  

A NeuroD1 AAV‐Based Gene Therapy for Functional Brain Repair in Alzheimer's Disease‐Like Non‐Human Primate Model

open access: yesAdvanced Science, EarlyView.
This study tests NeuroD1 AAV‐based gene therapy in a non‐human primate Alzheimer's disease model. The therapy prevents neuronal damage, inhibits hippocampal atrophy, and reduces neuroinflammation. It also repairs vascular and blood‐brain barrier damage, restores cerebrospinal fluid biomarkers, enhances hippocampal glucose metabolism, and improves ...
Zhouquan Jiang   +21 more
wiley   +1 more source

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