Results 181 to 190 of about 364,087 (292)
Differential modulation of CXCL8 versus CXCL10, by cytokines, PPAR-gamma, or PPAR-alpha agonists, in primary cells from Graves' disease and ophthalmopathy
, 2019 Silvia Martina Ferrari, Francesca Ragusa, Sabrina Rosaria Paparo, Francesco Nasini, Marco Nardi, Stefano Sellari Franceschini, Poupak Fallahi, Alessandro Antonelli +7 moreopenalex +2 more sourcesSteap4 Promotes Senile Osteoporosis via Fe2+‐ROS/C/EBPβ Feedback‐Driven Ferroptosis and Adipogenesis in Senescent BMSCs
Advanced Science, EarlyView.Senescent bone marrow mesenchymal stem cells (BMSCs) exhibit increased sensitivity to ferroptosis, a phenomenon associated with Steap4, a nicotinamide adenine dinucleotide phosphate hydrogen (NADPH)‐dependent metalloreductase that reduces Fe3+ to Fe2+.Liangliang Wang, Guangrong Yin, Wenming Li, Maoyuan Li, Feng Lu, Chao Xu, Gongyin Zhao, Dechun Geng, Jiaxiang Bai, Yuji Wang +9 morewiley +1 more sourcePrediction of fetal Graves’ disease among pregnant women with Graves’ disease who have undergone thyroidectomy or radioactive iodine therapy: A retrospective observational study
A. Hosoda, Naoko Arata, Nagayoshi Umehara, Shiori Sato, Akiko Sankoda, Yuko Iimura, Asako Mito, Chie Nagata, Seiji Wada, Haruna Kawaguchi, Masako Waguri, Nobuaki Mitsuda, Hitoshi Shimano +12 moreopenalex +2 more sourcesA Novel FGFR3‐Targeting Antibody‐Drug Conjugate Induces Tumor Cell Apoptosis through the cGAS–STING Pathway in Bladder Cancer
Advanced Science, EarlyView.LZU‐WZLYCS01 is a novel FGFR3‐targeting ADC for bladder cancer with 7‐ethyl‐9‐fluorocamptothecin (A2) as its cytotoxic payload. LZU‐WZLYCS01 intracellularly releases A2, which targets MAD2L1 to activate the cGAS‐STING pathway and induce tumor cell apoptosis.Shu Cui, Xiongfei Luo, Guangrui Fan, Jingqi Jiang, Yingru Wang, Enguang Yang, Jinpeng Ma, Ze Zhang, Yuhan Wang, Juan Wang, Dengtuo Wang, Hanzhang Wang, Liang Cheng, Junqiang Tian, Zhilong Dong, Yingqian Liu, Zhiping Wang +16 morewiley +1 more sourceHuman Atlas of Tooth Decay Progression: Identification of Cellular Mechanisms Driving the Switch from Dental Pulp Repair Toward Irreversible Pulpitis
Advanced Science, EarlyView.Tooth decay progression transforms the dental pulp response from repair to fibrosis. At early stages, stromal cells reprogram to repair the extra cellular matrix (ECM), blood vessels, and nerves, remodel and grow, keeping repair possible. In advanced decay, hypoxia, and vessel regression, in complement with an immune switch, fuel nerve degeneration and Hoang Thai Ha, Sofya Kosmynina, Amandine Verocq, Keremsah Ozen, Ines Tekia, Hugo Bussy, Marie Ramirez, Dima Sabbah, Chloe Goemans, Valerie Vandenbempt, Esteban N. Gurzov, Sumeet Pal Singh, Nicolas Baeyens +12 morewiley +1 more source