Results 221 to 230 of about 364,087 (292)

Case: New-onset hyperthyroidism in an adolescent girl. Is it Graves' disease? [PDF]

Paediatr Child Health
Scantlebury G, Stewart L, Silva C.
europepmc   +1 more source

Spatial Transcriptomics and snRNA‐seq Expose CAF Niches Orchestrating Dual Stromal‐Immune Barriers in Hepatocellular Carcinoma

Advanced Science, EarlyView.
HmmyCAFs may form a triple immunosuppressive niche: possibly secrete ECM (POSTN, etc.) as physical barriers to block CD8⁺ T cells, induce CD8⁺ T exhaustion via those molecules, and use HIF‐1α‐driven metabolism to create acidic, nutrient‐poor microenvironments that suppress T cells.
Yingxue Li, Changxiang Huan, Haoting Sun, Wei Zhang, Zhen Guo, Chuanyu Li, Jia Yao, Zhiqi Zhang, Shizhe Yu, Qiongzhu Dong, Lunxiu Qin, Jinze Li, Lianqun Zhou   +12 more
wiley   +1 more source

Effect of radioiodine treatment for Graves' disease on the generation of TSH anti-receptor stimulating antibodies (TSI). [PDF]

Arch Endocrinol Metab
Fiorin LB, Kasamatsu TS, Camacho CP, Furuzawa GK, Furlaneto M, Castiglioni MLV, Matsumura LK, Furlanetto RP, Batista MC, Maciel RMB, Ferreira CES, Janovsky CCPS, Martins JRM.   +12 more
europepmc   +1 more source

Biomechanical Phenotyping Reveals Unique Mechanobiological Signatures of Early‐Onset Colorectal Cancer

Advanced Science, EarlyView.
This study identifies a unique physical signature of colorectal cancer in younger adults: their tissues are mechanically stiffer than those in older patients with the same cancer. Furthermore, stromal remodeling in early‐onset colorectal cancer promotes epithelial mechanotransduction and proliferation, showing how mechanical alterations in the tissue ...
Nicole C. Huning, Munir H. Buhaya, Victor V. Nguyen, Afeefah Khazi‐Syed, Haider A. Ali, Adil Khan, Angela Fan, Robert C. Fisher, Zhikai Chi, Indu Raman, Guangchun Chen, Chengsong Zhu, Mengxi Yu, Andrew R. Jamieson, Sara Roccabianca, Victor D. Varner, Cheryl M. Lewis, Emina H. Huang, Jacopo Ferruzzi   +18 more
wiley   +1 more source

The evolving therapeutic landscape of Graves' disease in adults: present and future. [PDF]

Eur Thyroid J
Stan MN, Dosiou C.
europepmc   +1 more source

An in vitro model for thyroid autoimmunity [PDF]

, 1987
AM McGregor, BM Balfour, EM Allen, H Asamer, HR Harach, J Furszyfer, JE Fradkin, KW Wenzel, M Londei, N Bagchi, R Vollweider, T Hafanusa, TC Evans   +12 more
core   +1 more source

The association of HLA-DRB1, and-DQB1 genotypes in patients with graves' disease

, 2007
Wanwimon Yindee
openalex   +1 more source

Stromal Cell‐Mast Cell Communication Orchestrates Anti‐Viral Immunity in the Meninges

Advanced Science, EarlyView.
This study delineates the spatial distribution and postnatal maturation of meningeal mast cells and uncovers their essential role in antiviral immunity. Using genetic models, mast cells are shown to promote CD8⁺ T cell infiltration and viral clearance via IL‐33 receptor signaling and synergistic activation by IL‐33 and ATP from infected stromal cells ...
Qingqing Li, Weijia Chen, Mengxue Sun, Xinbo Ni, Qishan Ran, Xiaoyu Hu, Fang Cao, Wenwen Zeng   +7 more
wiley   +1 more source

A Case of Graves' Disease Exacerbation Triggered by BNT162b2 Vaccination. [PDF]

Cureus
Iwamoto H, Kimura T, Nakao E, Tatsumi F, Kaneto H.   +4 more
europepmc   +1 more source

Single‐Cell Nucleus Extraction with Cellular Indexing

Advanced Science, EarlyView.
VacTrap is a multilayer, high‐throughput microfluidic system that isolates and spatially indexes single nuclei from hundreds of cells within minutes. Using dissolvable hydrogel trapdoors triggered by chemical and vacuum actuation, VacTrap synchronously transfers nuclei while preserving spatial links to parent cells.
Trinh Lam, Ana Esmeralda Gomez Martinez, Alison Su, Anna Fomitcheva‐Khartchenko, Xin Wang, Md Nazibul Islam, Paul Lum, Amy Elizabeth Herr   +7 more
wiley   +1 more source