Results 111 to 120 of about 278,227 (245)

Orbital pseudotumour masquerading as Wegener’s granulomatosis [PDF]

open access: yes, 2015
A twenty-two year old female patient presented with new onset bilateral hard orbital masses and progressively worse tear lake problems. Computed tomography of the orbits revealed poorly differentiated bilateral orbital masses.
Fenech, Matthew, Fenech, Thomas
core  

Morphometric analysis of eyelid fissure in patients with eyelid retraction in acute stage of dysthyroid orbitopathy after treatment with botulinum toxin type A [PDF]

open access: yes, 2008
OBJETIVO: Apresentar dados morfométricos da fenda palpebral, antes e após a aplicação da toxina botulínica tipo A em pacientes com retração palpebral na fase aguda da orbitopatia distireoidiana.
COSTA, Patrícia Grativol   +3 more
core   +2 more sources

Intracellular Sphingosine‐1‐Phosphate Induces Lipolysis Through Direct Activation of Protein Kinase C Zeta

open access: yesThe FASEB Journal, Volume 39, Issue 7, 15 April 2025.
We have identified intracellular S1P as a direct activator of PKC zeta, leading to potent activation of lipolysis in 3T3‐L1 and primary adipocytes in vitro, while inhibition of S1P degradation by blocking S1P lyase through VD‐78 further enhances this effect.
Sarah Weske   +12 more
wiley   +1 more source

Graves′ orbitopathy: Management of difficult cases

open access: yesIndian Journal of Endocrinology and Metabolism, 2012
Management of Graves′ ophthalmopathy (GO) is based on three pillars: to stop smoking, to restore and maintain euthyroidism, and to treat the eye changes according to severity and activity of GO.
Wilmar M Wiersinga
doaj   +1 more source

Does thyroid surgery for Graves' disease improve health-related quality of life? [PDF]

open access: yes, 2012
PURPOSE: Graves' disease can induce alterations of the psychosocial well-being that negatively influence the overall well-being of patients. Among the current treatments, surgery has limited indications, and its impact on the health-related quality of ...
AMODIO, Emanuele   +6 more
core   +1 more source

Analysis of Cost and Treatment Effects in the Care Given for Graves' Disease: A Swedish Cost–Utility Analysis

open access: yesEndocrinology, Diabetes &Metabolism, Volume 8, Issue 2, March 2025.
Surgery was more cost‐effective than RAI when ablative treatment is advocated. Prediction score for recurrence directing patients to earlier Tx is cost‐effective and enables the introduction of a specialist thyroid nurse. Health economic evaluations should accompany future guidelines.
Lars Lindholm   +22 more
wiley   +1 more source

The psychosocial and clinical outcomes following orbital decompression surgery for thyroid eye disease and predictors of change in quality of life [PDF]

open access: yes, 2015
Objective: Thyroid eye disease (TED) has been found to reduce quality of life for many patients due to changes in their appearance and vision, although some appear to adjust better than others. This study was designed to investigate whether a patient’s
Ezra, D. G.   +5 more
core   +1 more source

The Role of miR‐144 in Inflammatory Diseases: A Review

open access: yesImmunity, Inflammation and Disease, Volume 13, Issue 3, March 2025.
In most cases, the expression of miR‐144 was downregulated, and it exerted corresponding biological effects by negatively regulating downstream target genes. Our reviews show that miR‐144 has the potential to become a diagnostic biomarker and therapeutic target for various inflammatory diseases. ABSTRACT Background Inflammation, often caused by various
Shukun Hong, Hongye Wang, Lujun Qiao
wiley   +1 more source

Graves’ orbitopathy as a rare disease in Europe: a European Group on Graves’ Orbitopathy (EUGOGO) position statement

open access: yesOrphanet Journal of Rare Diseases, 2017
Background Graves’ orbitopathy (GO) is an autoimmune condition, which is associated with poor clinical outcomes including impaired quality of life and socio-economic status.
P. Perros   +23 more
doaj   +1 more source

Effect of Botulinum Toxin-A Injection on Intraocular Pressure and Proptosis in Thyroid Associated Orbitopathy [PDF]

open access: yes, 2009
The aim of this study was to evaluate the effects of extraocular muscle injection of botulinum toxin-A (BTX-A) on intraocular pressure (IOP) and proptosis in patients with ocular motility disturbances in thyroid associated orbitopathy (TAO).
Davor Galetović   +6 more
core   +1 more source

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