Results 121 to 130 of about 64,260 (308)

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

open access: yesAdvanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak   +9 more
wiley   +1 more source

Takotsubo Cardiomyopathy and Graves’ Disease

open access: yes, 2016
While Graves’ disease has been a well-known clinical entity for some time, takotsubo cardiomyopathy (TTC) has become recognised as an acute heart failure syndrome only in recent years.
Rainer Zbinden, Damian Gruber
core   +1 more source

TSPYL5 Promotes Triple‐Negative Breast Cancer Metastasis by Antagonizing USP10‐Mediated PTEN Stabilization to Unleash a ZEB1‐Dependent EMT Program

open access: yesAdvanced Science, EarlyView.
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi   +8 more
wiley   +1 more source

Family-Based Association Study of Cytotoxic T-Lymphocyte Antigen-4 with Susceptibility to Graves' Disease in Han Population of Taiwan

open access: yes, 2011
Graves' disease (GD) is a common organ-specific autoimmune disorder inherited as a complex trait. Although there has not been consensus regarding the genuine susceptibility alleles, many population-based genetic studies showed association of the ...
CHEN, PEI-LUNG;FANN, CATHY SHENG-JIUAN;CHANG, CHIEN-CHING;WU, I-LIN;CHIU, WEI-YIH;LIN, CHIN- YU;YANG, WEI-SHIUNG;CHANG, TIEN-CHUN   +1 more
core   +1 more source

Macrophage Extracellular Traps in Immunity and Cancer

open access: yesAdvanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li   +5 more
wiley   +1 more source

Thyroid malignancies in patients with Graves' disease [PDF]

open access: yes, 2016
Amaç: Graves' hastalığı otoimmün bir tiroid hastalığıdır. Eş zamanlı primer tiroid maligniteleri ile Graves' hastalığı birlikteliği, giderek artan bir sıklıkta bildirilmektedir.
Güçer, Hasan
core  

The immunogenetics of Graves' disease

open access: yes, 1999
Graves' disease clusters in families, and higher concordance rates in monozygotic compared with dizygotic twins support a genetic basis to the disease.
Gough, SCL
core   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

open access: yesAdvanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu   +7 more
wiley   +1 more source

Extensive thyroidectomy in Graves' disease.

open access: yes, 2006
BACKGROUND: The best surgical treatment for hyperthyroidism caused by Graves' disease remains a controversial subject. METHODS: Seven hundred fourteen consecutive patients underwent total or near-total thyroidectomy for Graves' disease in a 13-year ...
Jublanc, Christelle   +7 more
core   +1 more source

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