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Best Practice & Research Clinical Endocrinology & Metabolism, 2014
Graves' disease is an autoimmune disorder resulting from thyrotropin receptor stimulation by autoantibodies. It may occur at any age during childhood, but its frequency increases with age, peaking during adolescence. Symptoms and signs are often recognizable and proportional to the increase in serum free thyroid hormone levels.
Juliane, Léger +3 more
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Graves' disease is an autoimmune disorder resulting from thyrotropin receptor stimulation by autoantibodies. It may occur at any age during childhood, but its frequency increases with age, peaking during adolescence. Symptoms and signs are often recognizable and proportional to the increase in serum free thyroid hormone levels.
Juliane, Léger +3 more
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The Journal of Clinical Endocrinology & Metabolism, 1964
The syndrome that is now commonly called neonatal Graves’ disease, i.e., hyperthyroidism of limited duration and occasionally associated with goiter and ophthalmopathy, was first reported in 1910 (1), followed by a case presentation in 1912 (2). Until 1974 an additional 75 cases were described (3) and since then the number has approximately doubled. As
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The syndrome that is now commonly called neonatal Graves’ disease, i.e., hyperthyroidism of limited duration and occasionally associated with goiter and ophthalmopathy, was first reported in 1910 (1), followed by a case presentation in 1912 (2). Until 1974 an additional 75 cases were described (3) and since then the number has approximately doubled. As
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The American Journal of Medicine, 1977
Graves' disease has recently been shown to exist in a euthyroid form in untreated patients. Sporadic reports of a hypothyroid form are beginning to emerge, thus illustrating the multifaceted nature of this disorder, with thyrotoxicosis at one end of the spectrum and hypothyroidism at the other.
J H, Christy, R S, Morse
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Graves' disease has recently been shown to exist in a euthyroid form in untreated patients. Sporadic reports of a hypothyroid form are beginning to emerge, thus illustrating the multifaceted nature of this disorder, with thyrotoxicosis at one end of the spectrum and hypothyroidism at the other.
J H, Christy, R S, Morse
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Journal of Pediatric Nursing, 2014
Hyperthyroidism is a rare but serious disease in children (Leger & Carel, 2013; Namwongprom, Unachak, Dejkamron, Ua-apisitwong, & Ekmahachai, 2013), characterized by overactivity of the thyroid gland that leads to elevation in circulating total and free thyroxine (T4) and tri-iodothyronine (T3) hormone levels, as well as metabolic acceleration in ...
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Hyperthyroidism is a rare but serious disease in children (Leger & Carel, 2013; Namwongprom, Unachak, Dejkamron, Ua-apisitwong, & Ekmahachai, 2013), characterized by overactivity of the thyroid gland that leads to elevation in circulating total and free thyroxine (T4) and tri-iodothyronine (T3) hormone levels, as well as metabolic acceleration in ...
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The Pathogenesis of Graves’ Disease
Endocrine Practice, 1995We have hypothesized over many years that Graves' disease (GD) and the other autoimmune thyroid diseases (AITD) are each due to antigen-specific defects in suppressor (regulatory) T lymphocyte function. There have been several reports dealing with the role of regulatory T lymphocyte subsets, ie., that will prevent autoimmune disease in these and other ...
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Annals of Internal Medicine, 1992
Excerpt Hyperthyroid Graves disease is an autoimmune disorder characterized by thyrotoxicosis, diffuse goiter, and antibodies directed against the thyrotropin (TSH) receptor, thyroglobulin (Tg), an...
S A, Ebner +3 more
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Excerpt Hyperthyroid Graves disease is an autoimmune disorder characterized by thyrotoxicosis, diffuse goiter, and antibodies directed against the thyrotropin (TSH) receptor, thyroglobulin (Tg), an...
S A, Ebner +3 more
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1977
Publisher Summary This chapter presents a study on the distribution of the long-acting thyroid stimulator (LATS), assay of human thyroid-stimulating IgG in five species, immune-electrophoresis patterns of fractions of serum protein obtained by isoelectric focusing, cytochemical bioassay of LATS, and relationship of thyroid-stimulating IgG to ...
J M, McKenzie, M, Zakarija
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Publisher Summary This chapter presents a study on the distribution of the long-acting thyroid stimulator (LATS), assay of human thyroid-stimulating IgG in five species, immune-electrophoresis patterns of fractions of serum protein obtained by isoelectric focusing, cytochemical bioassay of LATS, and relationship of thyroid-stimulating IgG to ...
J M, McKenzie, M, Zakarija
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The Ophthalmopathy of Graves' Disease
Medical Clinics of North America, 1991Fortunately, most patients with thyroid-related eye disease have mild ocular involvement that spontaneously involutes. Less than 5% of patients with hyperthyroidism will develop sufficiently severe ocular abnormalities that will require surgical intervention. Most patients with thyroid eye findings should be symptomatically managed.
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Medical Clinics of North America, 1975
J M, McKenzie, M, Zakarija, M, Bonnyns
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J M, McKenzie, M, Zakarija, M, Bonnyns
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2022 Update on Clinical Management of Graves Disease and Thyroid Eye Disease
Endocrinology and Metabolism Clinics of North America, 2022Thanh D Hoang, Henry B Burch
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