Programmed Cell Death-Ligand 1 (PD-L1) gene Single Nucleotide Polymorphism in Graves’ Disease and Hashimoto’s Thyroiditis in Korean Patients [PDF]
Endocrinology and Metabolism, 2021 Background Programmed cell death-ligand 1 (PD-L1) has an important role in regulating immune reactions by binding to programmed death 1 (PD-1) on immune cells, which could prevent the exacerbation of autoimmune thyroid disease (AITD).
Jee Hee Yoon +7 more
doaj +1 more source
The Pecularities of Correlation Between Insulin Resistance, Carbohydrate and Lipid Metabolism Indices in Patients with Graves'disease [PDF]
, 2017 Aim. The number of patients with endocrine disorders in the world, in particular, Graves' disease is continuously increasing. Recent studies have determined the fact of insulin resistance in thyroid disorders.
Kikhtyak, O. (Olesya) +2 more
core +2 more sources
Antithyroid Drug Treatment in Graves’ Disease [PDF]
Endocrinology and Metabolism, 2021 Graves’ disease is associated with thyrotropin (TSH) receptor stimulating antibody, for which there is no therapeutic agent. This disease is currently treated through inhibition of thyroid hormone synthesis or destruction of the thyroid gland. Recurrence
Jae Hoon Chung
doaj +1 more source
Statistical testing of shared genetic control for potentially related traits [PDF]
Genetic Epidemiology 37 (2013) 802-813, 2013 Integration of data from genome-wide single nucleotide polymorphism (SNP) association studies of different traits should allow researchers to disentangle the genetics of potentially related traits within individually associated regions. Formal statistical colocalisation testing of individual regions, which requires selection of a set of SNPs ...
arxiv +1 more source
Switching of Hashimoto Thyroiditis Into Graves’ Disease: A Case Report and Literature Review [PDF]
Disease and Diagnosis, 2021 Background: Hashimoto thyroiditis (HT) and Graves’ disease (GD) are autoimmune inflammatory thyroid disorders. The evolution from GD into HT is the most common scenario while the conversion from HT into GD seems to be less common. Case Presentation: A 20-
Rajab Maksoud +3 more
doaj +1 more source
Antigen receptor variable region repertoires expressed by T cells infiltrating thyroid, retroorbital, and pretibial tissue in Graves' disease [PDF]
, 1996 To date, it has remained unclear whether T cells infiltrating thyroid, retroorbital, and pretibial tissue of patients with Graves' ophthalmopathy and pretibial dermopathy represent a primary immune response that is directed against certain antigenic ...
Heufelder, Armin E. +2 more
core +1 more source
Rituximab in the treatment of Graves’ orbitopathy: latest updates and perspectives
Endocrine Connections, 2022 Graves’ orbitopathy (GO) is a potentially sight-threatening and disfiguring, extrathyroidal manifestation of Graves’ disease. It often impairs patients’ qu ality of life, causing severe social and psychological sequelae.
Jakub Supronik +3 more
doaj +1 more source
Thyroid Research, 2019 Background Treatment of moderate to severe Graves’ orbitopathy (GO) is based mainly on intravenous pulses of methylprednisolone. High doses of methylprednisolone can exert several adverse effects, some of which might be life-threatening. The objective of
Dorota Walasik-Szemplińska +2 more
doaj +1 more source
A Lightweight Blockchain and Fog-enabled Secure Remote Patient Monitoring System [PDF]
, 2023 IoT has enabled the rapid growth of smart remote healthcare applications. These IoT-based remote healthcare applications deliver fast and preventive medical services to patients at risk or with chronic diseases. However, ensuring data security and patient privacy while exchanging sensitive medical data among medical IoT devices is still a significant ...
arxiv +1 more source
Indian Journal of Endocrinology and Metabolism, 2019 Aims and Objective: We aimed to compare serum vitamin D level in new onset Graves' disease versus age and sex matched controls. Furthermore, we assessed the correlation of vitamin D with hormonal parameters and antibody titers in Graves' disease ...
Swayamsidha Mangaraj +5 more
doaj +1 more source