Results 71 to 80 of about 1,961,603 (303)

A 3D Human Neuron‐on‐Chip Platform to Monitor Neuronal Injury Responses

Advanced Healthcare Materials, EarlyView.
This study presents a novel 3D Neuron‐on‐Chip model that can maintain human PSC‐derived excitatory prefrontal cortex neurons in 3D hydrogels and can be used to monitor neuronal injury responses over time. Results show injury‐induced acute neuronal excitotoxicity, declining neuronal connectivity, and the activation of a neurodegenerative, SASP‐like ...
Ruiping Tang, Charles‐Francois Latchoumane, Avi Chopra, Md Marzan Sarkar, Chunki Kim, Nathan Gonsalves, Hsueh‐Fu Wu, John C. Sentmanat, Alan Liu, Isha Mhatre‐Winters, Aditya Mishra, Andrei G. Fedorov, Jay M. Patel, Nadja Zeltner, Steven L. Stice, Jason R. Richardson, Lohitash Karumbaiah   +16 more
wiley   +1 more source

Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy

Advanced Healthcare Materials, Volume 15, Issue 31, 21 August 2026.
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima, Sarmila Majumder, Divya S. Patel, Chunyu Hu, Hong Li, Xin Huang, Kim Truc Nguyen, Jacob Doon‐Ralls, Chiranth K. Nagaraj, Mangesh D. Hade, Setty M. Magaña, Eswar Shankar, Xiaoli Zhang, Daniel G. Stover, Bhuvaneswari Ramaswamy, Eduardo Reátegui   +15 more
wiley   +1 more source

Influence of Feeding Structure on the Flow Field and Separation of Cyclone Column Separator

Kuangchan zonghe liyong
Cyclone column separator is a kind of high-efficiency separation equipment widely used in the field of gravity separation of fine-grained and has showed perfect separation effects for coarse coal slime and coal gasification slags. [Objective] In order to
Pengbo ZHAO, Jianchuan GAO, Lianping DONG, Runquan YANG, Panpan FAN, Jiancheng WANG   +5 more
doaj   +1 more source

A Modular Liver–Microbial Microfluidic Platform to Evaluate Therapeutic and Adverse Effects of Microbial Metabolites

Advanced Healthcare Materials, Volume 15, Issue 31, 21 August 2026.
This study introduces a modular microfluidic platform that connects liver cells with live microbes to mimic key aspects of the gut–liver interaction in steatosis. Using this system, both microbial metabolites and live bacteria significantly reduced fat accumulation in liver cells, but live microbes triggered inflammation and broader metabolic changes ...
Hsih‐Yin Tan, In Young Hwang, Nanthini Jayabalan, Hui Ling Lee, Louis Jun Ye Ong, Chwee Teck Lim, Matthew Wook Chang, Yi‐Chin Toh   +7 more
wiley   +1 more source

Intelligent Orthopedics: Machine Learning in Diagnosis of Bone Disease, Implants, and Bone Health Monitoring

Advanced Healthcare Materials, EarlyView.
Efficient recovery from traumatic or degenerative diseases is a great challenge, even after all the advancements in bone and cartilage regeneration. Machine learning (ML) algorithms have presented opportunities to enhance these aspects by accurately analyzing imaging data.
Maryam Kamaei, Hesam Mohammadi, Shamim Golafshan, Mojtaba Alehosseini, Mahsa Mohammadzadeh, Atefeh Golshirazi, Nasim Golafshan, Tatiane Eufrásio‐da‐Silva, Alireza Dolatshahi‐Pirouz, Gorka Orive   +9 more
wiley   +1 more source

Application of gravity separators for enrichment of South Chah-Palang tungsten ore [PDF]

International Journal of Mining and Geo-Engineering, 2016
In the present study, the possibility of concentrating tungsten-copper vein ore in South Chah-Palang was examined using gravity separators including Jig Machine (-2360+600 μm), shaking table (-600+120 μm), and multi-gravity separator (MGS) (-120 μm). The
Hamid Hedayati Sarab-shahrak, Mohammad Noaparast, Sied Ziaedin Shafaei Tonkaboni, Sied Mehdi Hosseini   +3 more
doaj  

A Lightweight, 3D‐Printable, Low‐Cost, “One‐Click” Dorsal Skin Window for High‐Quality Long‐Term Multimodal Subcutaneous Tumor Imaging

Advanced Healthcare Materials, Volume 15, Issue 31, 21 August 2026.
An innovative, lightweight 3D‐printed skinfold chamber system is presented for long‐term intravital imaging. This affordable, biocompatible platform simplifies surgical implantation and allows high‐resolution, multimodal visualization of the tumor microenvironment for up to four weeks.
Iván Cortés Domínguez, Xabier Morales Urteaga, Maider Esparza, Lucía Grande, Ainhoa Urbiola, Cristina Ederra, Tomas Muñoz Santoro, Beatrice Pinci, Alvaro Teijeira, Carlos Ortiz de Solórzano   +9 more
wiley   +1 more source

Encoded Cell‐Material Interactions to Reroute Cytokine Signaling for Regenerative Medicine

Advanced Healthcare Materials, EarlyView.
We present native MATRIX (Material Activated To Regulate Inducible gene eXpression), a co‐engineered material‐cell platform. Surfaces functionalized with antibodies for endogenous soluble ligands (e.g., IL‐1β or IL‐6) capture and immobilize ligands for presentation to a cognate, engineered synthetic Notch receptor, releasing a transcription factor (TF)
Zachary M. Eidman, Jhanvi Sharma, Joanne C. Lee, Nicholas F. Schulze, Hannah J. Brien, Kevin C. Corn, Marjan Rafat, Jonathan M. Brunger   +7 more
wiley   +1 more source

Separation of Copper-lead Mixed Minerals with High Oxidation in Southwest China

Kuangchan zonghe liyong
A lot of oxide ore was stockpiled and left unprocessed after it was peeled from sulfide ores on the weathered layer of a large-scale copper-lead deposit in the southwest area of Yunnan Province, due to its much lower beneficiability than the sulfide ore.
Yingjie CHEN, Tingfang XIE, Song ZHANG, Yongjun XIAN   +3 more
doaj   +1 more source

Separation of inclusion particles from aluminum melt by super gravity

工程科学学报, 2018
The increasing demand for high-quality aluminum alloys in the automobile industry and other manufacturing fields has motivated manufacturers to produce cleaner aluminum alloys. However, conventional methods can barely meet the cleanliness requirements of
SONG Gao-yang, SONG Bo, YANG Yu-hou, YANG Zhan-bing, LI Long-fei, MA Liang   +5 more
doaj   +1 more source