Results 51 to 60 of about 2,910,785 (256)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Gray matter axonal connectivity maps.

open access: yesFrontiers in Psychiatry, 2015
Structural brain connectivity is generally assessed through methods that rely on pre-defined regions of interest (e.g. Brodmann’s areas), thus preventing analyses that are largely free from a-priori anatomical assumptions.
Leonardo eBonilha   +4 more
doaj   +1 more source

Other title: Inset title: Entrance to Mobile Bay

open access: yes, 1887
Copyright, 1878, by O.W. Gray & Son; Bottom margin center: Philadelphia : O.W. Gray & Son; Right margin: 94, 95.; Prime meridians: Washington and Greenwich.; Shows Mobile and Birmingham Railway, established 1887.
Gray, Frank A.
core   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Robust Encryption of Quantum Medical Images

open access: yesIEEE Access, 2018
Security of medical media is important for patient safety and confidentiality. This paper proposes a framework for the chaos-based quantum encryption of healthcare images. In the framework, healthcare staff in one location send cipher images to the cloud.
Ahmed A. Abd El-Latif   +2 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Facial Expression Recognition Using Fusion Features Based on Center-Symmetric Local Octonary Pattern

open access: yesIEEE Access, 2019
A local feature descriptor has gained a lot of interest in many applications, such as image retrieval, texture classification, and face recognition. This paper proposes a novel local feature descriptor: center-symmetric local octonary pattern (CS-LOP ...
Min Hu   +5 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Face recognition algorithm based on attractive local second gradient contours

open access: yesDianxin kexue, 2021
In order to solve the problem that traditional LDP algorithms is difficult to balance the effectiveness of feature extraction and the stability of feature encoding, an attractive local second gradient contours (ALSGC) face feature extraction algorithm ...
Xueyi YE   +3 more
doaj   +2 more sources

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

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