Results 91 to 100 of about 260,650 (303)

Voxelwise meta-analysis of gray matter reduction in major depressive disorder [PDF]

, 2012
Background: Voxel-based morphometry (VBM) has been widely used in studies of major depressive disorder (MDD) and has provided cumulative evidence of gray matter abnormalities in patients relative to controls.
Li, Jun, Kuang, Wei-Hong, Gong, QY (reprint author), Sichuan Univ, W China Hosp, HMRRC, Dept Radiol, 37 Guo Xue Xiang, Chengdu 610041, Peoples R China., Liao, Yi, Huang, Xiao-Qi, Chan, Raymond C. K., Wu, Qi-Zhu, Du, Ming-Ying, Yue, Qiang, Mechelli, Andrea, Gong, Qi-Yong   +10 more
core  

Contrasting effects of vocabulary knowledge on temporal and parietal brain structure across lifespan [PDF]

, 2010
Using behavioral, structural, and functional imaging techniques, we demonstrate contrasting effects of vocabulary knowledge on temporal and parietal brain structure in 47 healthy volunteers who ranged in age from 7 to 73 years.
Thomas, Michael S.C., Harth, H., Roberto Filippi (5791322), Price, C.J., Michael S. C. Thomas (13204914), Fiona M. Richardson (16656885), Helen Harth (7158278), Cathy J. Price (10828437), Filippi, Roberto, Richardson, Fiona M.   +9 more
core   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Beefeater, Rites of Spring and Gray Matter concert flier, Food For Thought, Washington, D.C. - September 29, 1984 [PDF]

, 1984
Photocopy of an advertising flier promoting a concert by the Washington, D.C. punk band, Beefeater. The concert occurred on September 29, 1984 at Food For Thought, a restaurant/concert venue in Washington, D.C.
Squip, Tomas
core  

Reduced gray matter in the prefrontal cortex and hippocampus: a potential neuroanatomical feature of insomnia comorbid with anxiety

Frontiers in Psychiatry
BackgroundChronic insomnia disorder (CID) frequently comorbid with generalized anxiety disorder (GAD), and accurate identification of this comorbidity remains challenging.
Minghe Xu, Yanjie Zhou, Bei Feng, Kunlin Ni, Xinyu Li, Pan He, Qingzhu Zhao, Yu Fan, Li Xiao, Bing Yu   +9 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

P/Q-type calcium-channel blockade in the periaqueductal gray facilitates trigeminal nociception: a functional genetic link for migraine? [PDF]

, 2002
The discovery of mis-sense mutations in the alpha1A subunit of the P/Q-type calcium channel in patients with familial hemiplegic migraine indicates the potential involvement of dysfunctional ion channels in migraine.
Goadsby, PJ, Yolande E. Knight, Knight, Yolande E., Knight, YE, Goadsby, Peter J., Bartsch, Thorsten, Peter J. Goadsby, Kaube, Holger, Holger Kaube, Kaube, H, Thorsten Bartsch, Bartsch, T   +11 more
core   +1 more source

Gray matter morphology and pain-related disability in young adults with low back pain

NeuroImage
Structural neuroplasticity in the brain may contribute to the persistence of low back pain (LBP) symptoms and the disability associated with them. It is not known if structural adaptations are evident early in the lifespan in young adults with LBP.
Jo Armour Smith, Rongwen Tain, Isaac Chrisman, Kelli G. Sharp, Laura M Glynn, Linda R. Van Dillen, Jesse V. Jacobs, Steven C. Cramer   +7 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source