Results 81 to 90 of about 260,650 (303)

Microstructural abnormalities in white and gray matter in obese adolescents with and without type 2 diabetes [PDF]

Aims/hypotheses. In adults, type 2 diabetes and obesity have been associated with structural brain changes, even in the absence of dementia. Some evidence suggested similar changes in adolescents with type 2 diabetes but comparisons with a non-obese ...
Chechlacz, Magdalena, Higgs, Suzanne, Allen, Harriet A., Nouwen, Arie, Chambers, Alison L., Blissett, Jacqueline, Barrett, Timothy   +6 more
core   +1 more source

Gray Matters

Contemporary Literature
This brief focuses on long-term care (LTC) for older persons, emphasizing the areas where social protection and jobs are key to building and strengthening this agenda. While LTC is sometimes perceived as part of the health agenda, social protection programs and policies are crucial for providing and financing social care-related services.
  +5 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Gray Matter and Embrace concert flier, 9:30 Club, Washington, D.C., March 13, 1986 [PDF]

, 1986
Circa 1980s photocopy of a flier for a concert featuring the Washington, D.C. area punk bands Embrace and Gray Matter. The concert occurred at the 9:30 Club in Washington, D.C. on March 13, 1986.

core  

Gray matter NG2 cells display multiple Ca2+-signaling pathways and highly motile processes [PDF]

, 2011
NG2 cells, the fourth type of glia in the mammalian CNS, receive synaptic input from neurons. The function of this innervation is unknown yet. Postsynaptic changes in intracellular Ca2+-concentration ([Ca2+]i) might be a possible consequence. We employed
Steinhäuser, Christian, Julia Haseleu, Karram, Khalad, Frotscher, Michael, Alexandra Wyczynski, Christian Haberlandt, Jabs, Ronald, Michael Frotscher, Wyczynski, Alexandra, Trotter, Jacqueline, Seifert, Gerald, Khalad Karram, Jacqueline Trotter, Christian Steinhäuser, Gerald Seifert, Derouiche, Amin, Jörg Pohle, Pohle, Jörg, Haberlandt, Christian, Haseleu, Julia, Ronald Jabs, Amin Derouiche   +21 more
core   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Astrocyte heterogeneity in brain metastases

Molecular Oncology, EarlyView.
Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver, Neibla Priego, Manuel Valiente   +2 more
wiley   +1 more source

Gray Matter [PDF]

Gray Matter: 1. the material of the brain. 2. an expression naming an idea or situation held in shadow. This book tangles with the unknown, but also celebrates the seductive curiosity its mystery provokes--A love letter from the imagination to the ...
Wheeler, Susan., Michas-Martin, Sara.
core  

Rites of Spring, Gray Matter, King Face concert flier, Food For Thought, Washington, D.C., March 30, 1985 [PDF]

, 1985
Circa 1980s photocopy of a flier advertising a concert by the Washington, D.C. punk bands Rites of Spring, Gray Matter (spelled "Grey" on the flier) and King Face. The concert occurred at Food for Thought in Washington, D.C. on March 30, 1985.

core  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source