Results 51 to 60 of about 2,944,590 (202)
The accelerating influence of humans on mammalian macroecological patterns over the late Quaternary [PDF]
The transition of hominins to a largely meat-based diet ~1.8 million years ago led to the exploitation of other mammals for food and resources. As hominins, particularly archaic and modern humans, became increasingly abundant and dispersed across the ...
Elliott Smith, Rosemary E.+4 more
core +1 more source
Epizootiologic Parameters for Plague in Kazakhstan
Reliable estimates are lacking of key epizootiologic parameters for plague caused by Yersinia pestis infection in its natural reservoirs. We report results of a 3-year longitudinal study of plague dynamics in populations of a maintenance host, the great ...
Michael Begon+5 more
doaj +1 more source
Implantable Medical Devices, Biomaterials, and the Foreign Body Response: A Surgical Perspective
ABSTRACT Implantable medical devices improve quality of life and reduce mortality by restoring the form and function of the human body. Their biomaterial surface components in contact with tissues are, however, susceptible to the host's foreign body response, which drives inflammation and implant fibrous encapsulation.
Nikita Kalashnikov+2 more
wiley +1 more source
Estimating the predictive validity of diabetic animal models in rosiglitazone studies [PDF]
For therapeutic studies, predictive validity of animal models - arguably the most important feature of animal models in terms of human relevance - can be calculated retrospectively by obtaining data on treatment efficacy from human and animal trials ...
Olsson, IAS, Varga, OE, Zsíros, N
core +1 more source
Artificial Intelligence's Potential in Zoo Animal Welfare
Heat map visualization of enclosure space use by meerkats, generated by the artificial intelligence model described in the case study. ABSTRACT The thorough, objective, and regular assessment of animal welfare in zoos and aquariums is rapidly becoming an essential task for these institutions.
Matyas Liptovszky, Emily Polla
wiley +1 more source
The Reconstruction of Peripheral Auditory Circuit: Recent Advances and Future Challenges
This paper summarizes the potential of biomaterials, stem cells, and gene editing technologies in the regeneration of inner ear hair cells, spiral ganglion neurons, and inner ear organoids. Challenges and potential developments are discussed and explored.
Zhe Li+3 more
wiley +1 more source
Rational Design of Inner Ear Drug Delivery Systems
Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu+5 more
wiley +1 more source
The great gerbil (Rhombomys opimus) as a host for tick species in Gurbantunggut desert [PDF]
Gang Liu+8 more
openalex +1 more source
Emerging Therapeutic Strategies for Hearing Loss
Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han+9 more
wiley +1 more source
Animal escapology II: escape trajectory case studies [PDF]
Escape trajectories (ETs; measured as the angle relative to the direction of the threat) have been studied in many taxa using a variety of methodologies and definitions.
Bacon, Jonathan P+2 more
core +1 more source