Bioassay-Guided Assessment of Antioxidative, Anti-Inflammatory and Antimicrobial Activities of Extracts from Medicinal Plants via High-Performance Thin-Layer Chromatography [PDF]
Natural products and their analogues have contributed significantly to treatment options, especially for anti-inflammatory and infectious diseases. Thus, the primary objective of this work was to compare the bioactivity profiles of selected medicinal ...
Marko D. Jović +4 more
doaj +2 more sources
Effect of Soil-Applied Metabolic Modulators on the Accumulation of Specialized Metabolites in Chelidonium majus L. [PDF]
Various metabolic modulators have been widely used in recent years to increase the accumulation of desired secondary metabolites in medicinal plants, although most studies to date have focused on in vitro systems.
Maria Stasińska-Jakubas +5 more
doaj +2 more sources
Chelidonium majus L.: A Current Perspective on Isoquinoline Alkaloids, Emerging Phytochemicals, Alkaloid Biosynthesis, and Biological Activities [PDF]
Phytochemistry serves as a vital bridge between traditional medicinal knowledge and modern scientific research, with important implications for pharmaceutical and industrial applications.
Ramona Romanu +6 more
doaj +2 more sources
The vulnerary potential of botanical medicines in the treatment of bacterial pathologies in fish [PDF]
Background and Aim: The use of plant-based medicine in treating and preventing fish disease has become increasingly popular due to the resistance of bacterial pathogens to chemicals widely used in aquaculture.
Farida Nurzhanova +5 more
doaj +2 more sources
The Greater Celandine: Identification and Characterization of an Antimicrobial Peptide from <i>Chelidonium majus</i>. [PDF]
Chelidonium majus, known as Greater Celandine, is a latex-bearing plant that has been leveraged for its anticancer and antimicrobial properties. Herein, C. majus aerial tissue is mined for the presence of antimicrobial peptides. A highly abundant cysteine-rich peptide with a length of 25 amino acids, deemed CM-AMP1, is characterized through multiple ...
Sadecki PW +5 more
europepmc +3 more sources
Romanian Wild-Growing Chelidonium majus—An Emerging Approach to a Potential Antimicrobial Engineering Carrier System Based on AuNPs: In Vitro Investigation and Evaluation [PDF]
Novel nanotechnology based on herbal products aspires to be a high-performing therapeutic platform. This study reports the development of an original engineering carrier system that jointly combines the pharmacological action of Chelidonium majus and ...
Adina-Elena Segneanu +9 more
doaj +2 more sources
Hepatotoxicity induced by greater celandine (Chelidonium majus L.): a review of the literature. [PDF]
The available literature assessing Chelidonium majus L. (CM) hepatotoxicity potential, and its risk to benefit assessment has been reviewed in this paper. Identification of significant scientific literature was performed via the following research databases: Cochrane Central, Google Scholar, EMBASE, Medline, Science Direct, Scopus, Web of Science ...
PANTANO, FLAMINIA +6 more
openaire +4 more sources
The effect of greater celandine active ingredient chelidonine on isolated rat bladder and trachea smooth muscles and primary lung and kidney cell lines [PDF]
This study aims to explore the pharmacodynamics of chelidonine, the active ingredient in greater celandine (Chelidonium majus L.), on in vitro rat bladder and trachea tissue, and evaluate its cell protective effects on primary lung and kidney cell lines.
Emre ARSLANBAŞ +6 more
doaj +3 more sources
Effect of STW 5-II (Iberogast-N) on Tolerance to Gastric Gas in Patients With Functional Dyspepsia. The IBO-2 Study. [PDF]
In a parallel, placebo‐controlled study with direct gas infusion into the stomach, STW 5‐II reduced the perception of abdominal symptoms in patients with dyspepsia complaining of bloating when compared to placebo, with a minor effect on gas transit and evacuation, and no effect on visible abdominal distension.
Aguilar A +6 more
europepmc +2 more sources
Two treatment schemes (vinblastine and vinblastin in combination with sapogenin-like substance (SLS) isolated from the greater celandine seeds) were applied towards murine NK/Ly lymphoma, and their therapeutic effects were compared.
M. D. Lootsik +2 more
doaj +3 more sources

