Results 121 to 130 of about 5,157,697 (275)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Frequency-Domain Reverse-Time Migration with Analytic Green's Function for the Seismic Imaging of Shallow Water Column Structures in the Arctic Ocean. [PDF]
Sensors (Basel), 2023 Kang SG, Jang UG.
europepmc +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
On the efficient evaluation of the azimuthal Fourier components of the Green's function for Helmholtz's equation in cylindrical coordinates. [PDF]
J Comput Phys, 2022 Garritano J +3 more
europepmc +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Reactivity of anatase (001) surface from first-principles many-body Green's function theory. [PDF]
RSC Adv, 2022 Jin F, Zhao Z.
europepmc +1 more source
Green's function method with energy-independent vertex functions
, 1996 In conventional Green's function methods the vertex function T is generally energy dependent. However, a model-space Green's function method where the vertex function is manifestly energy independent can be formulated using energy-independent effective ...
Kuo T.T.S. +4 more
core +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Spectral properties of a double-quantum-dot structure: A causal Green's function approach
, 1999 Spectral properties of a double quantum dot (QD) structure are studied by a causal Green's function (GF) approach. The double QD system is modeled by an Anderson-type Hamiltonian in which both the intra- and interdot Coulomb interactions are taken into ...
You JQ,Chinese Acad Sci,Inst Semicond,Natl Lab Superlattices & Microstruct,POB 912,Beijing 100083,Peoples R China. +2 more
core
The layered medium Green's function - A new look
, 2001 This paper describes an alternate method to formulate the layered medium Green's function suitable for computational electromagnetics. The Green's function is symmetrized so that the reciprocity theorem becomes obvious.
Zhao, JS +5 more
core +1 more source