Results 131 to 140 of about 5,157,697 (275)
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
On Some Inequalities with Higher Fractional Orders
Fractal and FractionalThe novelty herein pertains to a class of fractional differential equations involving the Hadamard fractional derivative of higher order. Our investigation encompasses the fractional integral operator of a logarithmic function.
Lakhdar Ragoub
doaj +1 more source
On the existence of Green’s function [PDF]
Proceedings of the American Mathematical Society, 1952 openaire +1 more source
Source data of Green's function and figure files.
, 2019 In the article of " Universal Fermi-surface anisotropy renormalization for interacting Dirac fermions with long-range interactions", we present the analysis of the unequal time Green's function to find the renormalized energy as well as the anisotropy of
HO KIN TANG (4064254)
core +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Comments on the Green's function of a planar domain
, 2017 We study several quantities associated to the Green's function of a multiply connected domain in the complex plane. Among them are some intrinsic properties such as geodesics, curvature, and -cohomology of the capacity metric and critical points of the ...
Borah, Diganta +5 more
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Renormalized Singles Green's Function in the T-Matrix Approximation for Accurate Quasiparticle Energy Calculation. [PDF]
J Phys Chem Lett, 2021 Li J, Chen Z, Yang W.
europepmc +1 more source
Green's function methods in heavy ion shielding [PDF]
, 1993 An analytic solution to the heavy ion transport in terms of Green's function is used to generate a highly efficient computer code for space applications. The efficiency of the computer code is accomplished by a nonperturbative technique extending Green's
Wilson, John W. +3 more
core
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source