Results 151 to 160 of about 55,033 (326)
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
Absolute and convective ion beam instability studied through Green's function [PDF]
V.O. Jensen+2 more
openalex +1 more source
On the existence of Green’s function [PDF]
openaire +2 more sources
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald+18 more
wiley +1 more source
Dynamics of a console cylindrical panel
A one-dimensional stationary problem of the dynamics of a console circular panel with applied normal pressure has been discussed. The boundary value problem has been considered for various shells, such as the Kirchhoff–Love shell and the Donnel–Mushtari ...
A.V. Ivanilov, D.V. Tarlakovskii
doaj
A Green's function convergence principle, with applications to computation and norm estimates [PDF]
G. B. Gustafson
openalex +1 more source
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach+8 more
wiley +1 more source
?Dyadic Green's functions for cylindrical waveguides with moving media? [PDF]
Carl F. Stubenrauch, C-T. Tai
openalex +1 more source
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche+8 more
wiley +1 more source
The Green's function for periodic differential difference equations
James C. Lillo
openalex +1 more source