Results 41 to 50 of about 4,825 (248)
Linear ODE with nonlocal boundary conditions and Green’s functions for such problems
In this article we investigate a formula for the Green’s function for the n-order linear differential equation with n additional conditions. We use this formula for calculating the Green’s function for problems with nonlocal boundary conditions.
Svetlana Roman, Artūras Štikonas
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
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ON GREEN’S FUNCTION OF DARBOUX PROBLEM FOR HYPERBOLIC EQUATION
It is well known that the Darboux problem for the hyperbolic equation is correct, both in the senseof classical and generalized solutions. An integral form of the solution of the Darboux problem ina characteristic triangle for a general two-dimensional ...
M. A. Sadybekov, B. Derbissaly
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Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The thermal transient load of the primary loop nuclear pipeline will cause fatigue damage at sensitive locations.And cumulative fatigue damage factors of these sensitive locations need to be monitored during the life extension of the nuclear power plant ...
WANG WeiWei +4 more
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In this paper the question on unconditional basicity of the system of eigenfunctions of the involutive perturbed Sturm-Liouville operator is investigated.
A.A. Sarsenbi
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The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
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The frequency-domain free-surface Green’s function method is widely used in solving ship hydrodynamic problems, with its core challenge lying in the computation of the Green’s function and its partial derivatives.
Minmin Zheng +5 more
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Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source

