Results 61 to 70 of about 5,157,697 (275)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Jixie qiangdu, 2020 The thermal transient load of the primary loop nuclear pipeline will cause fatigue damage at sensitive locations.And cumulative fatigue damage factors of these sensitive locations need to be monitored during the life extension of the nuclear power plant ...
WANG WeiWei +4 more
doaj
Қарағанды университетінің хабаршысы. Математика сериясы, 2018 In this paper the question on unconditional basicity of the system of eigenfunctions of the involutive perturbed Sturm-Liouville operator is investigated.
A.A. Sarsenbi
doaj +1 more source
ON GREEN’S FUNCTION OF DARBOUX PROBLEM FOR HYPERBOLIC EQUATION
Вестник КазНУ. Серия математика, механика, информатика, 2021 It is well known that the Darboux problem for the hyperbolic equation is correct, both in the senseof classical and generalized solutions. An integral form of the solution of the Darboux problem ina characteristic triangle for a general two-dimensional ...
M. A. Sadybekov, B. Derbissaly
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Some thermal properties of ideal gas
European Physical Journal C: Particles and FieldsIn this article, we investigate the thermal properties of non-relativistic many-body systems at finite temperatures and chemical potential. We compute the one-point function of various operators constructed out of the basic fields in ideal bosonic and ...
Rajesh Kumar Gupta, Meenu
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Journal of Marine Science and EngineeringThe frequency-domain free-surface Green’s function method is widely used in solving ship hydrodynamic problems, with its core challenge lying in the computation of the Green’s function and its partial derivatives.
Minmin Zheng +5 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source