Results 61 to 70 of about 4,825 (248)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Green’s function approach to the non-relativistic radial wavefunction using Hulthen potential

Physics Letters B
An approximate analytical solution to the radial Schrodinger equation for the generalized Hulthen potential is derived using a modified centrifugal term approximation method.
Adithya Anil, Praveen P. DSouza, Vipin Naik  N․S․, Antony Prakash Monteiro, K.B. Vijaya Kumar   +4 more
doaj   +1 more source

A Novel Scheme with FG-FFT for Analysis of Electromagnetic Scattering from Large Objects

International Journal of Antennas and Propagation, 2017
The replacement values to the singularity of fitting Green’s function are intensively researched in Fitting Green’s function Fast Fourier Transformation (FG-FFT).
Jia-Ye Xie, Guang Yu, Li-Li Pang, Wei-Bin Kong, Zhi-Xiang Huang   +4 more
doaj   +1 more source

Green’s Function of a Dressed Particle [PDF]

Physical Review Letters, 2006
We present a new, highly efficient yet accurate approximation for the Green's functions of dressed particles, using the Holstein polaron as an example. Instead of summing a subclass of diagrams (e.g. the non-crossed ones, in the self-consistent Born approximation (SCBA)), we sum all the diagrams, but with each diagram averaged over its free propagators'
openaire   +3 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Green's function topology of Majorana wires

New Journal of Physics, 2013
We represent the $\mathbb {Z}_2$ topological invariant characterizing a one-dimensional topological superconductor using a Wess–Zumino–Witten dimensional extension. The invariant is formulated in terms of the single-particle Green's function which allows
Jan Carl Budich, Björn Trauzettel
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Green's function based finite element formulations for isotropic seepage analysis with free surface

Latin American Journal of Solids and Structures
A solution procedure using the Green's function based finite element method (FEM) is presented for two-dimensional nonlinear steady-state seepage analysis with the presence of free surface in isotropic dams.
Hui Wang, Ya-Ting Gao, Qing-Hua Qin
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Deep Generalized Green's Function

Journal of Computational Physics
In this study, we address the challenge of obtaining a Green's function operator for linear partial differential equations (PDEs). The Green's function is well-sought after due to its ability to directly map inputs to solutions, bypassing the need for common numerical methods such as finite difference and finite elements methods.
Rixi Peng, Juncheng Dong, Jordan M. Malof, Willie J. Padilla, Vahid Tarokh   +4 more
openaire   +2 more sources