Results 101 to 110 of about 8,328 (212)
The Local Formulation for the Modified Green's Function Method
The Modified Global Green's Function Method (MGGFM) is an integral technique that is characterized by good accuracy in the evaluation of boundary fluxes.
Renato Barbieri +1 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
On the existence of Green’s function in Riemannian manifolds
This note provides a sufficient condition of geometric character for the existence of Green’s function in an arbitrary complete Riemannian manifold.
José L. Fernández
core +1 more source
STRONG SHORT-RANGE INTERACTIONS IN ONE-DIMENSIONAL PROTON CONDUCTOR
The behaviour of one-dimensional proton conductor is investigated on the basis of orientational-tunnelling model. The previously proposed technique which permits the proton interactions to be taken into account in the zero-order Hamiltonian, and is based
I.V.Stasyuk, O.Vorobyov
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
THE ALL-SOURCE GREEN’S FUNCTION AND ITS APPLICATIONS TO TSUNAMI PROBLEMS [PDF]
The classical Green’s function provides the global linear response to impulse forcing at a particular source location. It is a type of one-source-all-receiver Green’s function.
ZHIGANG XU
doaj
REDUCED p-MODULUS, p-HARMONIC RADIUS AND p-HARMONIC GREEN’S MAPPINGS
We consider the definitions and properties of the metric characteristics of the spatial domains previously introduced by the author, and their connection with the class of mappings, the particular case of which are the harmonic Green’s mappings ...
B. E. Levitskii
doaj +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
On the Lp-Integrability of Green’s function for Elliptic Operators
In this thesis, we discuss some of the results that were proven by Fabes and Stroock in 1984. Our main purpose is to give a self-contained presentation of the proof of this results.
Alharbi, Abdulrahman
core +1 more source

