Results 81 to 90 of about 137,035 (279)
Green's function based finite element formulations for isotropic seepage analysis with free surface
A solution procedure using the Green's function based finite element method (FEM) is presented for two-dimensional nonlinear steady-state seepage analysis with the presence of free surface in isotropic dams.
Hui Wang, Ya-Ting Gao, Qing-Hua Qin
doaj +1 more source
Discretized Thermal Green's Functions
We present a spectral weight conserving formalism for Fermionic thermal Green's functions that are discretized in imaginary time and thus periodic in imaginary ("Matsubara") frequency. The formalism requires a generalization of the Dyson equation and the
Georges +8 more
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The Green's function method has applications in several fields in Physics, from classical differential equations to quantum many-body problems. In the quantum context, Green's functions are correlation functions, from which it is possible to extract ...
Mariana M. Odashima +2 more
doaj +1 more source
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
The Green's functions for the Broadwell Model in a half space problem
We study an initial boundary value problem for the Broadwellmodel with a supersonic physical boundary. The Green's function for an initialvalue problem is constructed and its detailed pointwise structure is obtainedthrough the novel decompositions ...
Chiu-Ya Lan, Huey-Er Lin, Shih-Hsien Yu
doaj +1 more source
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
In this paper, the replacement values to the singularity of fitting Green's function are intensively researched in Fitting Green's function Fast Fourier Transformation (FG-FFT) for different frequency points.
Wei-Bin Kong +5 more
doaj +1 more source

