Results 51 to 60 of about 40,942 (260)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Integración conceptual Green-Lean en el diseño, planificación y construcción de proyectos Green-Lean conceptual integration in the project design, planning and construction

Revista Ingeniería de Construcción, 2009
El actual escenario de competitividad en el que se mueven las empresas de ingeniería, demanda nuevos enfoques de producción, donde las variables medioambientales juegan un papel relevante. En este sentido el concepto de sustentabilidad debe empezar a ser
Patricia Martinez, Vicente González, Eduardo Fonseca   +2 more
doaj  

"Implementing Green Manufacturing at Sewing Room in Medium Garment Factories Using Lean six Sigma"

Journal of Architecture, Art & Humanistic Science, 2018
Green Manufacturing is the renewal of production processes and the creation of environmentally friendly processes, in this paper we define "Green Manufacturing" as reducing defects in the medium garment factories through the re-evaluation of all stages ...
Ahmed Al Barbary
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Fuzzy Adoption of Lean and Green Paradigms on Freight Logistics [PDF]

Journal of Economic and Social Development (Varaždin)
The green logistics industry has the propensity to contribute to overall supply chain operationalisation and economic growth. The confluence of lean practices and green initiative paradigms for logistics activities minimises operational costs and ...
Dr Thokozani Patmond Mbhele
doaj  

Integration of Analytic Network Process in Adaptive Lean and Green Processing

Chemical Engineering Transactions, 2019
The manufacturing and processing industry have been an important part of the global economy. Many industry players are constantly looking for an alternative to improve their operation and environmental performance to remain competitive in the market. The
Wei Dong Leong, Bing Shen How, Sin Yong Teng, Sue Lin Ngan, Wendy Pei Qin Ng, Chun Hsion Lim, Hon Loong Lam, Chee Pin Tan, S.G. Ponnambalam   +8 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Modelling relationships between agility, lean, resilient, green practices in cold supply chains using ISM approach

Technological and Economic Development of Economy, 2020
This study aims at identifying the key agile, lean, resilient and green practices that influence capability of cold supply chain (CSC) using Interpretive Structural Modelling (ISM) technique.
Abbas Al-Refaie, Mohammad Al-Tahat, Natalija Lepkova   +2 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source