Results 61 to 70 of about 40,942 (260)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Integrated Lean and Green Management for Sustainable Organizational Performance: A Review [PDF]

EPJ Web of Conferences
The coexistence of operational efficiency and environmental responsibility has led scholars and practitioners to study the integration of lean manufacturing and green management.
Joshi Ajay Anantrao, Nerkar Pravin S.
doaj   +1 more source

Study and structural modeling of barriers in green lean implementation

International Journal For Multidisciplinary Research
The study explores the concept of Green Lean, which combines operational efficiency with environmental sustainability. Although interest in this approach is rising, practical implementation and related challenges are not well understood. This research identifies key barriers to Green Lean adoption and uses Interpretive Structural Modeling (ISM) to ...
Shalini Singh, Mohit Singhal, Vipul Parmarthi   +2 more
openaire   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Towards sustainability through Green, Lean and Six Sigma integration at service industry: review and framework

Technological and Economic Development of Economy, 2018
In the last decades, sustainable development has increasingly gained importance to service industry and the integration between Green, Lean and Six Sigma approaches in service systems is necessary in order to balance the need for operational efficiency ...
Rodrigo Caiado, Daniel Nascimento, Osvaldo Quelhas, Guilherme Tortorella, Luis Rangel   +4 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Leveraging Lean and Green Supply Chain Practices for Sustainable Supply Chain Performance: The Moderating Role of Environmental Orientation

Engineering Management in Production and Services
This study investigates the impact of lean and green supply chain practices on business process performance and sustainable supply chain performance. The research utilises the resource-based view (RBV) theory to construct a conceptual model wherein lean ...
Aladaileh Mohammad J., Aladayleh Khaled J., Lahuerta-Otero Eva, Cordero-Gutiérrez Rebeca   +3 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

The Green Lean Amine Machine: Harvesting Electric Power While Capturing Carbon Dioxide from Breath. [PDF]

Adv Sci (Weinh), 2021
Kalkus TJ, Guha A, Scholten PBV, Nagornii D, Coskun A, Ianiro A, Mayer M.   +6 more
europepmc   +1 more source