Results 141 to 150 of about 137,997 (282)

Green chemical processes: developments in research and education Green chemical processing ;, vol. 2./ edited by Mark Anthony Benvenuto.

open access: yes, 2017
Collection of articles previously published in the journal Physical sciences reviews.In English.Includes bibliographical references and index.The "greening" of industry processes - i.e., making them more sustainable - is a popular and often lucrative ...
Benvenuto (Mark Anthony),
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

A comparative evaluation of analytical green metrics for microextraction techniques based on polymeric and gel membranes as solid support

open access: yes
Sample preparation plays a pivotal role in chemical analysis, serving to isolate target analytes from diverse matrices and enhance measurement selectivity and sensitivity. This review examines microextraction's eco-friendliness versus tradition, focusing
Dorabadizare, Farzaneh   +4 more
core   +1 more source

Review on Green Analytical Chemistry

open access: yes
Green Analytical Chemistry (GAC) is a growing branch of chemistry that applies green chemistry principles to analytical methods to protect the environment and human health. Its main goal is to design safer and sustainable analytical procedures that use fewer and less harmful chemicals, consume less energy, and produce very little waste, while still ...
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Green analytical chemistry in gabapentin analysis: Methods and sustainability review

open access: yes
Gabapentin (GP), widely prescribed for seizures and neuropathic pain, requires effective therapeutic monitoring and pharmaceutical quality control.
Hemanth Kumar Chanduluru   +6 more
core   +1 more source

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