Results 121 to 130 of about 3,647,193 (357)

Metagenomics enables the first detection of Trypanosoma sp. in Streblidae (Diptera: Hippoboscoidea) parasitizing bats in São Paulo, Brazil

open access: yesFrontiers in Systems Biology
IntroductionBats play important ecological roles but can also harbor a wide diversity of pathogens, including trypanosomatids. Knowledge about the circulation of Trypanosoma spp.
Roberta Marcatti   +10 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Chloroplast phylogenomics provides new evidence for reevaluating the taxonomic placement of medicinal Agapetes

open access: yesFrontiers in Plant Science
Species of Agapetes are recognized for their radish-like tubers, which possess significant medicinal properties. Resolving the long-standing phylogenetic controversies between Agapetes and its relatives is crucial for facilitating the utilization of this
Jindong Wang   +17 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Simulating crowding of urban green areas to manage access during lockdowns. [PDF]

open access: yesLandsc Urban Plan, 2022
Geneletti D, Cortinovis C, Zardo L.
europepmc   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

PLANNING OF GREEN AREAS IN CITY AREAS

open access: yes
The rapid development of the city in vertical and horizontal directions sharply reduces the attractiveness of the landscape of the area. Interesting natural objects - parks, beautiful hills, banks of rivers and lakes, terraces on the plain, if they are preserved and organically included in the system of urban green spaces, in forming the environment of
openaire   +2 more sources

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