Results 211 to 220 of about 14,918,973 (360)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Should India invest more in less-favored areas?: [PDF]

open access: yes
Developing countries have to allocate limited government resources for rural areas among different investment activities and regions to achieve the twin goals of productivity growth and poverty alleviation.
Fan, Shenggen, Hazell, P. B. R.
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Correction: Genome-wide identification, structural characterization and expression profiling of AP2/ERF gene family in bayberry (Myrica rubra)

open access: yesBMC Plant Biology
Yumeng Liu   +8 more
doaj   +1 more source

Is living near green areas beneficial to mental health? Results of the Pró-Saúde Study. [PDF]

open access: yesRev Saude Publica, 2019
Barreto PA   +4 more
europepmc   +1 more source

Pursuing Green Growth: Some Conflicts and Necessary Conditions for a Pragmatic Environmental Policy [PDF]

open access: yes
This paper focusses narrowly on three areas of public policy concerning the environment deemed necessary for sustainable economic growth. It has relevance to Asian nations as they continue to demand for higher growth and at the same time keeping ...
Euston Quah
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Policy instruments as a trigger for urban sprawl deceleration: monitoring the stability and transformations of green areas. [PDF]

open access: yesSci Rep
Filepné Kovács K   +8 more
europepmc   +1 more source

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