Results 91 to 100 of about 818,018 (265)

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Green HRM, Green In-Role Behavior, Green Extra-Role Behavior: The Moderating Role of Green Leadership in the Higher Education Sector of Pakistan

open access: yesSustainable Business and Society in Emerging Economies
Purpose: The study aims to investigate how Green Human Resource Management (GHRM) affects employees’ green in-role and extra-role behavior and to examine the moderating effect of green leadership on this relationship in universities in Khyber Pakhtunkhwa, Pakistan.
Naseer Muhammad   +3 more
openaire   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Integrating Religiosity and Public Policy to Foster Green Behavior: A Muslim Perspective

open access: yesJournal of Islamic Economic Laws
Plastic pollution has become one of the most pressing environmental challenges of our time, yet the role of faith and knowledge in driving sustainable consumer behavior remains underexplored.
Qoshid Al Hadi
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Effects of Green Human Resource Management on Green Innovation in Pakistani Textile Industries: The Mediating Effect of Green Behavior

open access: yesBusiness Review
In the textile sector, employees' green behavior and green innovation are currently receiving more attention as contributing factors. Consequently, firms are launching a variety of sustainable development initiatives and developing green business plans ...
Saeeda Mirza, Shazia Parveen
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Environmentally Friendly Behavior of Islamic Bank Employees: The Role of Islamic Banks in Maintaining Sustainability

open access: yesEconomica: Jurnal Ekonomi Islam
The challenges of climate change and the recent energy crisis have increased the importance of environmental sustainability, with green technology emerging as a key driver of sustainable growth.
Fajar Adhitya   +2 more
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

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