Results 81 to 90 of about 2,682,027 (282)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Identifying Green Bonds Impact on Company Reputation and Risk

open access: yesInternational Research Journal of Business Studies
In recent years, there has been a growing awareness of the severity of climate-related risks, prompting a global imperative for environmental preservation.
Widya Estiningrum, Zaäfri Ananto Husodo
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

I Green Bond: caratteri peculiari nella loro recente evoluzione regolamentare e di mercato

open access: yes, 2022
Negli ultimi anni il mercato dei Green Bond è cresciuto molto rapida-mente e anche la composizione delle relative emissioni si è evoluta note-volmente nel tempo.
Maria Cristina Quirici
core  

Climate policy uncertainty and green bond markets

open access: yesEnvironmental Research Communications
Using monthly data from July 2013 to April 2023, this study applies a time-varying causality approach to examine the relationship between climate policy uncertainty and the green bond market.
Omer Serkan Gulal   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Time-Frequency Connectedness between Green Bonds and Conventional Financial Markets: Evidence from China

open access: yesDiscrete Dynamics in Nature and Society
This paper examines the dynamic evolution and volatility spillovers between China’s green bond market and conventional financial markets (bond, stock, commodity, and foreign exchange markets) using time and frequency connectedness measures. The empirical
Yingliang Chen   +2 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

The value of being green: Assessing the impact of green bond issuance on stock prices of European listed companies

open access: yesInternational Review of Economics & Finance
Green bonds have become increasingly important financial instruments for financing sustainable development, with Europe leading global issuance. Using data on 1122 green bond issuances by European listed companies between 2013 and 2024, we examine the ...
Radosław Pietrzyk   +3 more
doaj   +1 more source

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