Results 111 to 120 of about 2,699,204 (288)

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Experimental investigation of thermal and mechanical characteristics of slag cement mortars with PCM for radiant floors

open access: yesCase Studies in Construction Materials
Mortar thermal storage layers incorporating phase change material (PCM) can improve the thermal performance of radiant floors in buildings, reduce indoor temperature fluctuations and thus provide further savings in building heating energy consumption ...
Guo Li, Guoqiang Xu, Jintao Zhang
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

A comprehensive review on green buildings research: bibliometric analysis during 1998-2018. [PDF]

open access: yesEnviron Sci Pollut Res Int, 2021
Li Y   +5 more
europepmc   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

Development trend of green residential buildings in China under the guidance of the low-carbon concept: A policy review and analysis

open access: yesJournal of Urban Management
To achieve China's “carbon peaking and carbon neutrality'' goals, the benign development of green residential buildings plays an indispensable role. The result of green residential buildings in China has accumulated a wealth of experience.
Jiajing Wu, Xiaoyu Ying
doaj   +1 more source

Evaluation of financial incentives for green buildings in Canadian landscape. [PDF]

open access: yesRenew Sustain Energy Rev, 2021
Rana A   +4 more
europepmc   +1 more source

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