Results 81 to 90 of about 816,580 (291)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
A New Manhattan Project for Clean Energy Independence [PDF]
Seven “grand challenges” for the next five years: plug-in electric cars and trucks, carbon capture, solar power, nuclear waste, advanced biofuels, green buildings, and fusionalternative energy, plug-in electric cars, carbon capture, solar power, nuclear ...
Lamar Alexander
core
Development of modular green roofs for high-density urban cities [PDF]
, 2008 Stream A: Lifecyle of implementing green roofs and green wallsMany cities are facing problems of urban heat island and lack of greenery space. Green roofs can help mitigate the adverse effects and bring the nature back to the urban area.
Chan, HM, Hui, SCM
core
The European Green Deal after Corona: Implications for EU climate policy. CEPS policy Insights No 2020-06 / March 2020 [PDF]
, 2020 Climate change policy cannot be the first priority of the EU for the immediate future. However, in spite of the corona-crisis the urgency of climate change mitigation has not disappeared.
Catuti, Mihnea +5 more
core
ToxicsIdentifying environmental factors contributing to allergic asthma is critical for effective prevention. PM2.5, a major environmental pollutant, and high relative humidity frequently coexist in urban and industrialized regions, particularly when ...
Ziyu Shu +9 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Fostering energy efficiency dynamics through ex-ante strategic niche management: the UK perspective [PDF]
, 2013 The United Kingdom building sector has been challenged to retrofit a huge stock of existing buildings in order to increase its adaptive capacity for climate change impacts.
Goulding, Jack Steven +2 more
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Remarkable 3-in-1 Pakis-Stem Green Roofs for Saving Thermal Flat Rooftop [PDF]
, 2016 The green councils in the world are often promoting green buildings in terms of energy savings by mitigating the thermal load on buildings,especially thermal rooftop, into the room. Green roofs can be the most effective to lower roof thermal in tropical
Canadarma, Wanda Widigdo +2 more
core +1 more source