Results 101 to 110 of about 3,015,856 (249)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Emiliana Lione of West Australian Ballet, March 2004 [picture] /
, 2004 Part of collection: Jon Green collection of photographs of Australian dancers and choreographers.; Title supplied by photographer.; Image from Jon Green's private collection 'avec attitude'.; Acquired in digital format; access copy available online ...
Green, Jon.
core
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
SESAR 3 ER 1 Green-GEAR – D5.1 – Initial OSED – Green RC
Green-GEAR aims at enabling and incentivising optimum green trajectories and airspace use through new ATM procedures; it develops three new SESAR Solutions to this end.
Bolic, T.
core +1 more source
Melissa Aurisch of West Australian Ballet, November 2003 [picture] /
, 2004 Part of collection: Jon Green collection of photographs of Australian dancers and choreographers.; Title supplied by photographer.; Image from Jon Green's private collection 'avec attitude'.; Acquired in digital format; access copy available online ...
Green, Jon.
core
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Selective RGB Channel Jittering for Robust Endoscopic Disease Detection Across Multiple Lesion Types
Sakarya University Journal of Computer and Information SciencesDeep learning has significantly advanced medical image analysis, particularly in the field of endoscopic images. However, these advancements are constrained by the availability of high-quality, annotated medical datasets.
Duygu Cakır
doaj +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Benazir Hussain of West Australian Ballet, May 2004 [picture] /
, 2004 Part of collection: Jon Green collection of photographs of Australian dancers and choreographers.; Title supplied by photographer.; Image from Jon Green's private collection 'avec attitude'.; Acquired in digital format; access copy available online ...
Green, Jon.
core
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source