Results 111 to 120 of about 3,352,793 (292)

Simon Dow in rehearsal for 'La Boheme', West Australian Ballet, 2004 [picture] /

open access: yes, 2004
Part of collection: Jon Green collection of photographs of Australian dancers and choreographers.; Title supplied by photographer.; Image from Jon Green's private collection, 'Avec attitude'.; Acquired in digital format; access copy available online ...
Green, Jon.
core  

Understanding the key drivers of and technology related issues associated with going multi-channel [PDF]

open access: yes, 2012
A multi-channel retail strategy is viewed by many academics and practitioners to be the success model for most retailers. Yet, while there are many drivers of, and advantages related to, using multiple channels to sell products and services to customers ...
Whysall, P   +5 more
core  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Selective RGB Channel Jittering for Robust Endoscopic Disease Detection Across Multiple Lesion Types

open access: yesSakarya University Journal of Computer and Information Sciences
Deep learning has significantly advanced medical image analysis, particularly in the field of endoscopic images. However, these advancements are constrained by the availability of high-quality, annotated medical datasets.
Duygu Cakır
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Callum Hastie of West Australian Ballet, April 2004 [picture] /

open access: yes, 2004
Part of collection: Jon Green collection of photographs of Australian dancers and choreographers.; Title supplied by photographer.; Image from Jon Green's private collection 'avec attitude'.; Acquired in digital format; access copy available online ...
Green, Jon.
core  

SESAR 3 ER 1 Green-GEAR – D5.1 – Initial OSED – Green RC

open access: yes
Green-GEAR aims at enabling and incentivising optimum green trajectories and airspace use through new ATM procedures; it develops three new SESAR Solutions to this end.
Bolic, T.
core   +3 more sources

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

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