Results 131 to 140 of about 1,541,834 (325)

Synthetic pathways and processes in green chemistry. Introductory overview [PDF]

open access: bronze, 2000
Pietro Tundo   +8 more
openalex   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Development of a Green Method for Amide Synthesis [PDF]

open access: yes, 2011
The aim of this work was to determine the scope and limitations of using microwave technology, solvent-free conditions and green chemistry-applicable solid supports for amide synthesis. We hypothesize that the method developed by Comerford et al [12] may
Darragh, Megan Ruth
core   +1 more source

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

open access: yesMolecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou   +13 more
wiley   +1 more source

Química verda: l'ús de lipases per a la producció de compostos d'interès industrial [PDF]

open access: yes, 2010
Una de les tendències en el camp de la química sostenible, la green chemistry, és la d'emprar biocatalitzadors en comptes de metalls pesants en la catàlisi de diferents reaccions químiques.
Gotor-Fernández, Vicente
core  

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

open access: yesMolecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou   +11 more
wiley   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Green chemistry. Sustaining a high-technology civilization [PDF]

open access: bronze, 2001
Anindya Ghosh   +14 more
openalex   +1 more source

Repurposing HFC-125 to tetrafluoroethylene: A step toward a more sustainable fluoropolymer feedstock strategy

open access: yesiScience
Summary: The urgency to reduce hydrofluorocarbon (HFC) emissions, particularly HFC-125 (pentafluoroethane, CF3CF2H), has driven efforts to develop sustainable alternatives. Herein, we present a method for converting HFC-125 into tetrafluoroethylene (TFE),
Hiroto Iwasaki   +4 more
doaj  

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