Results 81 to 90 of about 577,345 (292)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Green Chemistry

open access: yesInternational Journal for Research in Applied Science and Engineering Technology
Green Chemistry is the design of chemical processes and products which reduce or exclude the use and generation of poisonous, toxic, dangerous andbio-accumulative chemical substances. It's a new approach to scientifically grounded environmental protection and plays a vital part in controlling global warming, acid rain and climate change.
  +6 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Evaluating and managing the sustainability of investments in green and sustainable chemistry: An overview of sustainable finance approaches and tools

open access: yes, 2022
Green chemistry (GC) was developed to maximise resource efficiency and minimise hazards in chemical processes and products. Over time, the approach evolved into green and sustainable chemistry (GSC), which aims at promoting the development of an ...
YILAN, GÜLŞAH
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Dos primeiros aos segundos doze princípios da Química Verde

open access: yesQuímica Nova, 2012
The second 12 principles of Green Chemistry (Winterton, 2001) are presented and discussed to show how they press academic chemists to focus the invention of synthetic pathways more directly on industrial process development, allowing a quicker progress ...
Adélio A. S. C. Machado
doaj   +1 more source

Green Chemistry: Progress and Barriers

open access: yes, 2016
Green chemistry can advance both the health of the environment and the primary objectives of the chemical enterprise: to understand the behavior of chemical substances and to use that knowledge to make useful substances.
Green, Sarah A.
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Green metrics in Mechanochemistry

open access: yes, 2022
The development of new green methodologies and their broader adoption for promoting sustainable development in chemistry laboratories and industry play a significant role in society, due to the economic importance of chemistry and its and widespread ...
Nicolas, Fantozzi   +5 more
core   +1 more source

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